54079-68-4

Basic information

• Product Name: 4-Chloro-3-nitropyridine hydrochloride
• Synonyms: 54079-68-4;4-CHLORO-3-NITROPYRIDINE HYDROCHLORIDE;4-CHLORO-3-NITROPYRIDINE MONOHYDROCHLORIDE;4-Chloro-3-nitropyridineHCl;4-Chloro-3-nitropyridine HCl Salt;4-CHLORO-3-NITROPYRIDINE HYDROCHLORIDE, 90+%;4-Chloro-3-nitropyridine hydrochloride, 97+%;4-Chloro-3-nitropyridine hydrochloride, 98+%
• CAS NO: 54079-68-4
• Molecular Formula: C₅H₃ClN₂O₂*ClH
• Molecular Weight: 195
• EINECS: -0
• Product Categories: Pyridine
• Mol File: 54079-68-4.mol

Chemical Properties

• Melting Point: 135-138°C
• Boiling Point: 279.9 °C at 760 mmHg
• Flash Point: 279.9 °C at 760 mmHg
• Appearance: /
• Vapor Pressure: 0.00299mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Chloro-3-nitropyridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-3-nitropyridine hydrochloride(54079-68-4)
• EPA Substance Registry System: 4-Chloro-3-nitropyridine hydrochloride(54079-68-4)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2811
• PackingGroup: III
• Hazardous Substances Data: 54079-68-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
4-Chloro-3-nitropyridine hydrochloride is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4-Chloro-3-nitropyridine hydrochloride serves as a building block for the creation of pesticides and other agricultural chemicals. Its reactivity and functional groups make it suitable for the production of effective and targeted agrochemicals.
Used in Dye Manufacturing:
4-Chloro-3-nitropyridine hydrochloride is utilized in the manufacturing of dyes due to its ability to impart color. Its chemical properties allow it to be integrated into dye molecules, enhancing the colorfastness and performance of the dyes in various applications.
Used in Organic Synthesis:
As a versatile intermediate, 4-Chloro-3-nitropyridine hydrochloride is employed in organic synthesis for a wide range of chemical reactions. Its presence in various synthetic pathways enables the production of diverse chemical compounds, expanding the scope of organic chemistry.
Used in Laboratory Research:
4-Chloro-3-nitropyridine hydrochloride is used as a research compound in laboratories to study its properties and potential applications. Its water solubility and reactivity make it an ideal candidate for exploring new chemical reactions and understanding its behavior in different chemical environments.

InChI:InChI=1/C5H3ClN2O2.ClH/c6-4-1-2-7-3-5(4)8(9)10;/h1-3H;1H

Upstream product

• 5435-54-1 4-hydroxy-3-nitropyridine 

Downstream Products

• 1796-84-5 4-ethoxy-3-nitropyridine 
• 98130-83-7 3-nitro-4-thiocyanato-pyridine 
• 227473-79-2 4-(4-methoxyphenyl)-3-nitropyridine 
• 53406-38-5 1H-indol-1-amine 
• 357263-45-7 2-bromo-4-chloropyridin-3-amine 

Relevant articles and documents

Antiviral azaindole derivatives

The present invention is directed to a series of chemical entities that express HIV-1 inhibitory activities.

Pyrolysis of Aryl Azides. VI Identification of Neighbouring Group Effects in Pyrolysis of Azidopyridines and Azidoquinolines

Although there are literature reports of anomalous behaviour on pyrolysis of ortho-nitroazidopyridines and ortho-nitroazidoquinolines, we find that these compounds cyclize to the expected furazan 1-oxides in near-quantitative yields, and with a high degree of neighbouring group participation by the nitro group.Kinetic studies in decalin solution reveal the following rate enhancements by the ortho-nitro group: 3-azido-2-nitropyridine, 466 at least; 4-azido-3-nitropyridine, 5400; 4-azido-3,5-dinitropyridine, 640; 4-azido-3-nitroquinoline, 82.4; 5-azido-6-nitroquinoline,27.6; 2-nitro-1-azidonaphthalene, 12.7.The unstable furazan oxide, oxadiazolopyridine 1-oxide, has now been characterized. Oxadiazolopyridine 1-oxide decomposed in decalin at 145 deg to give products indicative of a nitrene intermediate.