227473-79-2Relevant academic research and scientific papers
C-H arylation of pyridines: High regioselectivity as a consequence of the electronic character of C-H bonds and heteroarene ring
Guo, Pengfei,Joo, Jung Min,Rakshit, Souvik,Sames, Dalibor
supporting information; experimental part, p. 16338 - 16341 (2011/11/29)
We report a new catalytic protocol for highly selective C-H arylation of pyridines containing common and synthetically versatile electron-withdrawing substituents (NO2, CN, F and Cl). The new protocol expands the scope of catalytic azine functi
Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
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Page 76, (2008/06/13)
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
Cross coupling strategies towards the synthesis of the streptonigrin CD moiety
Crous, Renier,Dwyer, Catherine,Holzapfel, Cedric W.
, p. 721 - 726 (2007/10/03)
An efficient route to an appropriate model of the streptonigrin 4- phenylpyridine CD moiety is reported. 4-Chloro-3-nitropyridine was found to be the key precursor and its reactivity in cross coupling reactions was further investigated.
