54429-56-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Bromoethanesulfonyl Chloride is used as a key intermediate for the synthesis of various drugs and pharmaceutical compounds. Its unique chemical structure allows for the development of new therapeutic agents with improved efficacy and safety profiles.
Used in Agrochemical Manufacturing:
In the agrochemical industry, 2-Bromoethanesulfonyl Chloride is employed as a building block for the synthesis of various agrochemicals, such as pesticides and herbicides. Its reactivity enables the creation of effective and targeted agrochemicals to protect crops and enhance agricultural productivity.
Used in Dye Production:
2-Bromoethanesulfonyl Chloride is utilized in the production of dyes, particularly in the synthesis of specific dye molecules. Its unique properties contribute to the development of dyes with enhanced colorfastness and stability.
Used in Fine Chemicals Synthesis:
In the synthesis of fine chemicals, 2-Bromoethanesulfonyl Chloride serves as a valuable building block. Its reactivity and versatility allow for the development of a wide range of specialty chemicals used in various applications, such as fragrances, flavorings, and other high-value products.
Safety Precautions:
Due to the hazardous nature of 2-Bromoethanesulfonyl Chloride, it is essential to handle and store it with extreme caution. Proper personal protective equipment (PPE), such as gloves, goggles, and lab coats, should be worn during its use. Additionally, it should be stored in a well-ventilated area, away from heat and ignition sources, to minimize the risk of accidents and exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 54429-56-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,4,2 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 54429-56:
(7*5)+(6*4)+(5*4)+(4*2)+(3*9)+(2*5)+(1*6)=130
130 % 10 = 0
So 54429-56-0 is a valid CAS Registry Number.
54429-56-0Relevant articles and documents
PHTHALAZINE AND PYRIDO [3,4-D] PYRIDAZ INE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS
-
Page/Page column 50, (2009/05/30)
The present invention relates to compounds of formula (I), and salts thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various diseases, such as allergic rhinitis.
Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside-CoA bisubstrates as mechanistic probes for aminoglycoside N-6′-acetyltransferase
Gao, Feng,Yan, Xuxu,Zahr, Omar,Larsen, Aaron,Vong, Kenward,Auclair, Karine
supporting information; experimental part, p. 5518 - 5522 (2009/05/30)
Aminoglycoside-coenzyme A conjugates are challenging synthetic targets because of the wealth of functional groups and high polarity of the starting materials. We previously reported a one-pot synthesis of amide-linked aminoglycoside-CoA bisubstrates. These molecules are nanomolar inhibitors of aminoglycoside N-6′-acetyltransferase Ii (AAC(6′)-Ii), an important enzyme involved in bacterial resistance to aminoglycoside antibiotics. We report here the synthesis and biological activity of five new aminoglycoside-CoA bisubstrates containing sulfonamide, sulfoxide, or sulfone groups. Interestingly, the sulfonamide-linked bisubstrate, which was expected to best mimic the tetrahedral intermediate, does not show improved inhibition when compared with amide-linked bisubstrates. On the other hand, most of the sulfone- and sulfoxide-containing bisubstrates prepared are nanomolar inhibitors of AAC(6′)-Ii.
