56175-44-1

Basic information

• Product Name: 1-METHOXY-2-INDANOL
• Synonyms: 1-METHOXY-2-INDANOL;1-METHOXY-2-INDANOL 98+%
• CAS NO: 56175-44-1
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• EINECS: 275-901-7
• Mol File: 56175-44-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 146-148 °C/11 mmHg(lit.)
• Flash Point: 113 °C
• Appearance: /
• Density: 1.128 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00233mmHg at 25°C
• Refractive Index: n20/D 1.548(lit.)
• CAS DataBase Reference: 1-METHOXY-2-INDANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHOXY-2-INDANOL(56175-44-1)
• EPA Substance Registry System: 1-METHOXY-2-INDANOL(56175-44-1)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R21/22:Harmful in contact with skin and if swallowed.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 56175-44-1(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR SLIGHTLY BROWNISH VISCOUS LIQUID

InChI:InChI=1/C10H12O2/c1-12-10-8-5-3-2-4-7(8)6-9(10)11/h2-5,9-11H,6H2,1H3/t9-,10+/m1/s1

Upstream product

• 95-13-6 1-indene 
• 67-56-1 methanol 
• 10368-44-2 trans-2-bromo-1-indanol 
• 124-41-4 sodium methylate 
• 768-22-9 2,3-epoxyindene 
• 768-22-9 (1aR,6aS)-6,6a-dihydro-1aH-indeno[1,2-b]oxirene 

Downstream Products

• 7480-35-5 (1S,2R)-1-amino-2-indanol 

Relevant articles and documents

A simple one-pot synthesis of β-alkoxy alcohols from alkenes

β-Methoxy alcohols are easily obtained from the one-pot reaction of alkenes with oxone in methanol, in the absence of any additive or catalyst. The use of other alcohols as solvents has shown that the efficiency of the process decreases with the steric hindrance of the alcohol.

FeCl3·6H2O supported on SiO2 catalysed ring opening of epoxides with alcohols, acetic acid, water, chloride, bromide and nitrate ions

FeCl3·6H2O absorbed on chromatographic silica gel can act as an efficient catalyst for alcoholysis, hydrolysis and acetolysis of epoxides. Methanolysis of (R)-styrene oxide proceeds with high stereospecificity and in excellent yield. This catalyst can also convert epoxides to their corresponding β-halohydrins and β-nitrato alcohols in the presence of chloride, bromide and nitrate ions respectively.

Highly efficient, regio- and stereoselective alcoholysis of epoxides catalyzed with iron(III) chloride

An efficient, catalytic, simple and mild method for the conversion of epoxides into their corresponding β-alkoxy alcohols was performed in primary, secondary and tertiary alcohols and in the presence of catalytic amounts of ferric chloride. The β-alkoxy alcohols were obtained with high stereo- and regioselectivity and in good to excellent yields.