56485-04-2

Basic information

• Product Name: 2-oxo-3-phenyl-propanal
• Synonyms: 2-oxo-3-phenyl-propanal;Benzylglyoxal [2-Oxo-2-phenylacetaldehyde] [Pyruvaldehyde, phenyl] [2-Oxo-3-phenylpropanal];Benzylglyoxal [2-Oxo-2-phenylacetaldehyde] [Pyruvaldehyde, phenyl] [2-Oxo-3-phenylpropal]
• CAS NO: 56485-04-2
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 148.15862
• Mol File: 56485-04-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 243.2°Cat760mmHg
• Flash Point: 91.2°C
• Appearance: /
• Density: 1.112g/cm³
• Vapor Pressure: 0.0325mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 2-oxo-3-phenyl-propanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-oxo-3-phenyl-propanal(56485-04-2)
• EPA Substance Registry System: 2-oxo-3-phenyl-propanal(56485-04-2)

Safety Data

• Hazardous Substances Data: 56485-04-2(Hazardous Substances Data)

Usage

General Description

2-oxo-3-phenyl-propanal, also known as phenylpyruvic acid, is a chemical compound with the molecular formula C9H8O2. It is a yellowish liquid with a sweet, floral odor, and is commonly used as a flavoring agent in the food industry. 2-oxo-3-phenyl-propanal is also found in nature and is produced by the human body as a metabolic byproduct of phenylalanine. The compound has been studied for its potential health benefits, including its antioxidant and anti-inflammatory properties. Additionally, it has been investigated for its potential as a precursor in the synthesis of pharmaceuticals and other organic compounds.

InChI:InChI=1/C9H8O2/c10-7-9(11)6-8-4-2-1-3-5-8/h1-5,7H,6H2

Upstream product

• 186581-53-3 diazomethane 
• 1638-63-7 2-acetoxy-2-phenylacetyl chloride 
• 7149-58-8 diethoxyacetic acid piperidinyl amide 
• 6921-34-2 benzylmagnesium chloride 
• 17173-38-5 1-acetoxy-3-diazo-1-phenyl-acetone 
• 20461-78-3 3-Diazo-1-methoxy-carbonyloxy-1-phenyl-aceton 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 77252-94-9 3-phenyl methylglyoxal dimethyl acetal 
• 4250-02-6 1-diazo-3-phenyl-2-propanone 
• 104-53-0 3-phenyl-propionaldehyde 

Downstream Products

• 19256-31-6 1,1-diethoxy-3-phenylpropane-2-one 
• 70217-82-2 2-benzyl-8-benzyl-6-(phenyl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 169614-76-0 6-benzyl-1,3-dimethyllumazine 
• 144448-54-4 2-benzyl-3-methoxy-6-(3'-nitrobenzylthio)imidazo<1,2-b>pyridazine 
• 144448-53-3 2-benzyl-3-methoxy-6-(2'-nitrobenzylthio)imidazo<1,2-b>pyridazine 
• 144448-55-5 2-benzyl-3-methoxy-6-(4'-nitrobenzylthio)imidazo<1,2-b>pyridazine 
• 144448-52-2 2-benzyl-6-(2',4'-dichlorobenzylthio)-3-methoxyimidazo<1,2-b>pyridazine 
• 144448-64-6 2-benzyl-6-(2',4'-dichlorophenoxy)-3-methoxyimidazo<1,2-b>pyridazine 
• 144448-43-1 2-benzyl-3-methoxy-6-(2'-methoxybenzylthio)imidazo<1,2-b>pyridazine 
• 144448-49-7 2-benzyl-6-(2'-chlorobenzylthio)-3-methoxyimidazo<1,2-b>pyridazine 
• 144448-65-7 2-benzyl-3-methoxy-6-(3'-methoxybenzylamino)imidazo<1,2-b>pyridazine 
• 144448-45-3 2-benzyl-3-methoxy-6-(4'-methoxybenzylthio)imidazo<1,2-b>pyridazine 
• 144448-44-2 2-benzyl-3-methoxy-6-(3'-methoxybenzylthio)imidazo<1,2-b>pyridazine 
• 144448-51-1 2-benzyl-6-(4'-chlorobenzylthio)-3-methoxyimidazo<1,2-b>pyridazine 

Relevant articles and documents

Luminescence-based methods and probes for measuring cytochrome P450 activity

The present invention provides methods, compositions, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferin or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. Upon addition of the luciferin derivative or other luminogenic molecule into a P450 reaction, the P450 enzyme metabolizes the molecule into a bioluminescent enzyme substrate, e.g., luciferin and/or luciferin derivative metabolite, in a P450 reaction. The resulting metabolite(s) serves as a substrate of the bioluminescent enzyme, e.g., luciferase, in a second light-generating reaction. Luminescent cytochrome P450 assays with low background signals and high sensitivity are disclosed and isoform selectivity is demonstrated. The present invention also provides an improved method for performing luciferase reactions which employs added pyrophosphatase to remove inorganic pyrophosphate, a luciferase inhibitor which may be present in the reaction mixture as a contaminant or may be generated during the reaction. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors.

Selenium-Mediated Conversion of Alkynes into α-Dicarbonyl Compounds

The reaction of terminal and internal alkynes with diphenyl diselenide and ammonium peroxydisulfate in methanol proceeds smoothly to give α-keto acetals and α-keto ketals, respectively.This one-pot procedure is suggested to proceed through the initial formation of phenylselenenyl sulfate, a strong electrophilic reagent which effects the methoxyselenenylation of the alkynes.The addition products thus formed suffer methoxydeselenenylation giving the observed products and regenerating the phenylselenenylating agent.In some cases the reaction can be carried out using only catalytic amounts of diphenyl diselenide.The same reaction carried out in the presence of water or of ethylene glycol gives the unprotected or the diprotected α-dicarbonyl compounds, respectively.