59352-90-8

Basic information

• Product Name: 2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE
• Synonyms: 5-BROMO-6-METHYL-PYRIDINE-2,3-DIAMINE;AKOS BBS-00004536;2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE;2,3-DIAMINO-5-BROMO-6-PICOLINE;2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE (2,3-DIAMINO-5-BROMO-6-PICOLINE);5-Bromo-2,3-diamino-6-picline;5-Bromo-6-methyl-2,3-pyridinediamine;2,3-Pyridinediamine, 5-bromo-6-methyl-
• CAS NO: 59352-90-8
• Molecular Formula: C₆H₈BrN₃
• Molecular Weight: 202.05
• EINECS: 261-714-8
• Product Categories: Pyridine
• Mol File: 59352-90-8.mol

Chemical Properties

• Melting Point: 134.0 to 138.0 °C
• Boiling Point: 311.2 °C at 760 mmHg
• Flash Point: 142 °C
• Appearance: Pale yellow to brown/Powder
• Density: 1.688 g/cm³
• Vapor Pressure: 0.000573mmHg at 25°C
• Refractive Index: 1.682
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: soluble in Methanol
• PKA: 4.68±0.50(Predicted)
• CAS DataBase Reference: 2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE(59352-90-8)
• EPA Substance Registry System: 2,3-DIAMINO-5-BROMO-6-METHYLPYRIDINE(59352-90-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• TSCA: Yes
• Hazardous Substances Data: 59352-90-8(Hazardous Substances Data)

Usage

Chemical Properties

Yellow to light yellow solid

InChI:InChI=1/C6H8BrN3/c1-3-4(7)2-5(8)6(9)10-3/h2H,8H2,1H3,(H2,9,10)

Upstream product

• 68957-50-6 2-amino-5-bromo-6-methyl-3-nitropyridine 
• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 1824-81-3 2-Amino-6-methylpyridine 

Downstream Products

• 28279-41-6 6-bromo-5-methylimidazo[4,5-b]pyridine 
• 120640-84-8 6-bromo-5-methyl-1H-[1,2,3]triazolo[4,5-b]pyridine 
• 27582-24-7 5-methylpyridol[2,3-d]imidazole 
• 27582-23-6 5-methyl-1H-[1,2,3]triazolo[4,5-b]pyridine 

Relevant articles and documents

IMIDAZOPYRIDIN-2-ONE DERIVATIVES

A compound represented by formula (I) having mTOR inhibitory activity or a pharmacologically acceptable salt thereof.

Improvement of the synthesis of 6-bromo-5-methylimidazo[4,5-b]pyridine, a stabilizer for color photography

Procedures were suggested for preparing 6-bromo-5-methylimidazo[4,5-b] pyridine, a stabilizer for TsMF-2 color photographic moment, a component of developing pastes of the photographic kit.

PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

Substituted pyridyl imidazole derivatives of formula (I) inhibit effectively the action of angiotensin II and have a superior anti-hypertensive activity. STR1

Pyridyl imidazole derivatives and processes for the preparation thereof

Novel pyridyl imidazole derivatives of formula(I) inhibit effectively the action of angiotensin II and have a superior antihypertensive activity: STR1 wherein: A is a straight, branched or cyclic C1 -C6 alkyl or alkenyl group, OR1 (wherein R1 is a hydrogen, or a straight, branched or cyclic C1 -C6 alkyl or alkenyl radical), or NR2 R3 (wherein R2 and R3 are independently a hydrogen, or a straight, branched or cyclic C1 -C6 alkyl radical); B is a group of the following formula STR2 D is a hydrogen; a halogen; a straight, branched or cyclic C1 -C6 alkyl, C2 -C6 alkenyl or C2 -C6 alkynyl group which is optionally substituted with OH, a C1 -C4 alkoxy radical, CO2 R1, COR1, CON(R1)2 or N(R1)2, wherein R1 is the same as defined above; tetrazol-5-yl; a perfluoro-C1 -C4 alkyl group; or N(R1)2, OR1, CO2 R1 or CON(R1)2, wherein R1 is the same as defined above; E is a hydrogen; a halogen; a straight or branched C1 -C6 alkyl, C2 -C6 alkenyl or C2 -C6 alkynyl group which is optionally substituted with OH, a C1 -C4 alkoxy radical, CO2 R1, COR1, CON(R1)2 or N(R1)2, wherein R1 is the same as defined above; a perfluoro-C1 -C4 alkyl group; NO2 ; or N(R1)2 or OR1, wherein R1 is the same as defined above; and n is 0 or an integer of 1 to 4.

Diaminopyridine compounds and methods of use

The present invention relates to compositions and method for inhibiting nonenzymatic cross-linking (protein aging) which contain diaminopyridines and derivates thereof. Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.