59433-50-0

Basic information

• Product Name: BOC-DL-PRO-OH
• Synonyms: PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;BOC-DL-PROLINE;BOC-DL-PRO-OH;1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID;AKOS 91525;N-BOC-DL-PROLINE;REF DUPL: Boc-DL-Pro-OH;1-(tert-butoxycarbonyl)proline [Boc-DL-Pro-OH]
• CAS NO: 59433-50-0
• Molecular Formula: C10H17NO4
• Molecular Weight: 215.25
• Product Categories: Boc-Amino Acids and Derivative;Boc-Amino acid series;Boc Amino Acids
• Mol File: 59433-50-0.mol

Chemical Properties

• Melting Point: 133-135°C
• Boiling Point: 337.2 °C at 760 mmHg
• Flash Point: 157.7 °C
• Appearance: /
• Density: 1.201 g/cm³
• Storage Temp.: 2-8°C
• PKA: 4.01±0.20(Predicted)
• CAS DataBase Reference: BOC-DL-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-DL-PRO-OH(59433-50-0)
• EPA Substance Registry System: BOC-DL-PRO-OH(59433-50-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 59433-50-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BOC-DL-PRO-OH is used as a reagent for the enantiospecific preparation of functionalized hindered triazolopyridinones. These triazolopyridinones are important intermediates in the synthesis of pharmaceutical compounds with potential therapeutic applications. The enantiospecific preparation ensures that the desired chiral centers are correctly formed, leading to the production of biologically active molecules.

Upstream product

• 13303-10-1 tert-Butyl 4-nitrophenyl carbonate 
• 147-85-3 L-proline 
• 124-38-9 carbon dioxide 
• 86953-79-9 tert-butyl pyrrolidine-1-carboxylate 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 69610-41-9 Boc-L-Pro-H 
• 36301-70-9 (S)?2?[(S)?1?carboxyethylcarbamoyl]pyrrolidine?1?carboxylic acid tert?butyl ester 
• 75-44-5 phosgene 
• 1907-33-1 lithium tert-butoxide 
• 34619-03-9 tert-butyldicarbonate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 98015-52-2 1,2,2,2-Tetrachloroethyl tert-Butyl Carbonate 
• 50739-44-1 1-(t-butoxycarbonyl)-1,2,4-triazolo<4,3-a>pyridinium-3-olate 

Downstream Products

• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 81771-37-1 Gly-Pro-Hyp-Gly-Ala-Gly 
• 24050-88-2 Boc-Pro-Phe-OPic 
• 60482-97-5 NT_10-13 
• 52071-65-5 N-tert-butyloxycarbonyl-L-prolyl-L-phenylalanine 
• 69038-47-7 Boc-L-Pro-L-Leu-OBzl 
• 95755-29-6 Boc-Pro-Δ-Leu-OMe 
• 110579-78-7 N-tert-butyloxycarbonyl-L-prolyl-L-methionine p-nitrophenyl ester 
• 101692-93-7 H-Pro-Val-OBzl 
• 132149-56-5 N-t-butyloxycarbonylprolyl-p-nitrophenylalanine 
• 125405-89-2 (S)-2-({[(S)-1-(Benzyloxycarbonylmethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 86645-64-9 iBuOCO-Lys(Z)-OMe 
• 112839-80-2 N^α--N^γ-(benzyloxycarbonyl)-L-lysine 
• 128120-96-7 N-t-Boc-proline-isoleucine phenacyl ester 

Relevant articles and documents

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