60335-70-8Relevant articles and documents
Synthetic method of aromatic rose ether perfume
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Paragraph 0031-0042, (2020/07/24)
The invention discloses a synthesis method of an aromatic rose ether perfume, which comprises the following steps: with benzaldehyde and isopentenol as raw materials and non-strong protonic acid or Lewis acid as a catalyst, completely carrying out a reaction in an inert non-protonic solvent at reflux temperature, and carrying out after-treatment on the obtained reaction mixed solution to obtain 4-methyl-2-phenyl-dihydropyran. According to the method disclosed by the invention, a mild catalyst is adopted; benzaldehyde or isopentenol with the equivalent weight smaller than 1 is used, a solvent azeotropic with water is used for removing water generated in the reaction, the reaction selectivity is improved, and the reaction molar yield can reach about 90%; the method has the advantages of being economical, environmentally friendly, easy and convenient to implement and high in yield and is suitable for large-scale industrial production.
Z-Selective ring opening of vinyl oxetanes with dialkyl dithiophosphate nucleophiles
Guo,Njardarson
, p. 10802 - 10804 (2013/11/06)
Dialkyl dithiophosphates selectively ring open vinyl oxetanes in excellent yields under mild reaction conditions to form useful allylic thiophosphate products with high Z-selectivity. The Royal Society of Chemistry 2013.
An efficient synthesis of dihydro- and tetrahydropyrans via oxonium-ene cyclization reaction
Bondalapati, Somasekhar,Reddy, Udagandla C.,Saha, Pipas,Saikia, Anil K.
experimental part, p. 3428 - 3438 (2011/06/20)
An efficient method has been developed for the synthesis of 2,3-dihydropyrans and 4-methylenetetrahydropyrans from aldehydes and substituted homoallyl alcohols in benzene mediated by boron trifluoride etherate in good yields. The reaction proceeds via oxonium-ene reaction.
REACTIONS ON A SURFACE. 1. CONDENSATION OF 3-METHYL-3-BUTEN-1-OL WITH CARBONYL COMPOUNDS ON SiO2 AND Al2O3
Ibatullin, U. G.,Pavlov, Yu. V.,Safarov, M. G.
, p. 1107 - 1109 (2007/10/02)
3-Methyl-3-buten-1-ol reacts with various aldehydes and ketones on silica gel and Al2O3 surfaces in the absence of solvents and conventional catalysts for this reaction to form derivatives of di- and tetrahydropyrans.
SYNTHESIS OF 4-METHYL-2,3,4-TRICHLOROTETRAHYDROPYRAN AND SEVERAL FEATURES OF THE STEREOCHEMISTRY OF THE NUCLEOPHILIC SUBSTITUTION OF THE α-CHLORINE ATOM
Gevorkyan, A.A.,Arakelyan, A.S.,Dvoryanchikov, A.I.
, p. 380 - 386 (2007/10/02)
A convenient method has been developed for the synthesis of 4-methyl-2,3,4-trichlorotetrahydropyran by the chlorination of 4-methyl-4-chlorotetrahydropyran, 4-methyl-5,6-dihydro-2H-pyran and its dichloride.A study was carried out on the reactions of 4-methyl-2,3,4-trichlorotetrahydropyran with alcohols, with sodium thiocyanate and Grignard reagents.PMR spectroscopy was used to study the stereochemistry of 4-methyl-2,3,4-trichlorotetrachloropyran and its derivatives, 2-substituted 4-methyl-3,4-dichlorotetrahydropyrans.The dechlorination of these dichloro derivatives by metallic sodium leads to 2,4-disubstituted 5,6-dihydro-2H-pyrans with high regioselectivity
PRODUCTION OF SUBSTITUTED 5,6- AND 3,6-DIHYDRO-2H-PYRANS FROM 4,4-DIMETHYL- AND 4-METHYL-4-PHENYL-1,3-DIOXANES AND CARBONYL COMPOUNDS
Romanov, N. A.,Kantor, E. A.,Musavirov, R. S.,Karakhanov, R. A.,Rakhmankulov, D. L.
, p. 1576 - 1581 (2007/10/02)
2,4-Disubstituted and 2,2,4-trisubstituted dihydropyrans, isomeric with respect to the position of the double bond, were obtained by the reaction of 4,4-dimethyl- and 4-methyl-4-phenyl-1,3-dioxanes with aldehydes and ketones.The effects of temperature and of the amount and nature of the catalyst on the direction and selectivity of the reaction were investigated.
