107-56-2

Usage

Uses

O,O-Diisopropyl Dithiophosphate is an intermediate in the synthesis of Bensulide (B166000), which is an organophosphate acetylcholinesterase inhibitor used as an herbicide (1) in the protection of crops through pesticides (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.

InChI:InChI=1/3C6H15O2PS2.Sb/c3*1-3-5-7-9(10,11)8-6-4-2;/h3*3-6H2,1-2H3,(H,10,11);/q;;;+3/p-3

Upstream product

• 67-63-0 isopropyl alcohol 
• 756-80-9 O,O-dimethyl phosphorodithioic acid 
• 108-88-3 toluene 
• 56-23-5 tetrachloromethane 
• 73479-00-2 octylsulfanylmethyl-oxirane 
• 1026872-43-4 diazabicyclo-octane 
• 142-96-1 dibutyl ether 
• 15857-57-5 tetraphosphorus decasulfide 
• 62-53-3 aniline 
• 105526-48-5 tris(diisopropoxyphosphinothioylthio)-s-triazine 

Downstream Products

• 20442-31-3 O,O,S-triisopropyl phosphorodithioate 
• 76538-05-1 disulfidothiophosphoric acid O,O'-diisopropyl ester-S-S-(2-nitro-phenyl ester) 
• 36624-64-3 dithiophosphoric acid O,O'-diisopropyl ester-S-phenethyl ester 
• 3031-21-8 bis(O,O-diisopropoxyphosphinothioyl)disulfide 
• 66078-55-5 N-(diisopropoxythiophosphoryl)thiobenzamide 
• 42461-48-3 O,O-Diisopropyl-S-(benzylformimidoyl)-dithiophosphonat 
• 5925-56-4 Dithiobenzoesaeure-isopropylester 
• 30978-51-9 Dithiophosphorsaeure-O,O-diisopropylester-S-<3-chlor-buten-(2)-ylester> 
• 3253-29-0 O,O,O,O-tetraisopropyl pyrophosphorotrithioate 
• 24420-17-5 S-acetyl O,O-diisopropyl phosphorodithioate 
• 2227-79-4 benzenecarbothioamide 
• 92351-18-3 diisopropyldithiophosphoric acid methyl ester 
• 40780-81-2 S-methyl thioimidate of benzoic acid 
• 128342-61-0 N-diisopropoxythiophosphoryl-S-methylbenzimidothioate 

Relevant academic research and scientific papers

Dialkyl (alkylene) dithiophosphate adducts of anhydrous stannous chloride: Synthesis, characterization, and biological activities

Dialkyl (alkylene) dithiophosphate adducts of stannous chloride were synthesized by the reaction of anhydrous tin(II) chloride (SnCl2) and dialkyl (alkylene) dithiophosphoric acid in a 1:1 molar ratio, under anhydrous reaction conditions, below 5 °C in a closed vessel. The newly synthesized adducts were characterized by physicochemical and spectroscopic techniques [FT-IR, NMR (1H, 31P, and 119Sn), and mass spectrometry]. Coordination modalities have indicated a donor-acceptor interaction between sulfur and tin(II) moieties, where tin(II) acts as a Lewis acid. The adducts were found to have significant antibacterial activity against Escherichia coli and Pseudomonas aeruginosa, and antifungal activity against Aspergillus niger and Candida albicans. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

13C and 31P Solid-State NMR Studies of Bis(dialkoxythiophosphoryl) Disulfides

The principal elements of the chemical shift tensors for the phosphorus atoms in three bis(dialkoxythiophosphoryl) disulfides were determined from both static and magic angle spinning NMR spectra, using the intensities of the peak in the spinning sidebands relative to those of the central band in the latter method.These studies show that it is possible to deduce a mode of molecular motion in the solid state by analysis of the shielding parameters.Variable-temperature 13C and 31P CP MAS NMR of these samples from 190 to 320 K revealed a peculiar motion of the methoxy group and a rigid P-S-S-P backbone for bis(dimethoxythiophosphoryl) disulf ide.In addition, these studies confirmed that it is possible to distinguish the different x-ray crystal structures from the solid-state NMR experiments.

Synthesis, spectral characterization and antibacterial activity of O, O’-dialkyl and alkylene dithiophosphatogold (III)dichloride; crystal structure of [S2POCMe2CMe2O]AuCl2

O, O’-Dialkyl and alkylene dithiophosphatogold (III)dichloride complexes of the type [(RO)2PS2]AuCl2 and [S2POGO]AuCl2, where R = Et, nPr, iPr, iBu, Ph, cyclohexyl and cyclopentyl, where G = CMe2CMe2-, have been synthesized in 80-90% yields by reaction of the corresponding acid or sodium salts of the appropriate dithiophosphoric acids in 1:1 ratio with gold (III) chloride in dry dichloromethane at room temperature. The compounds have been characterized by elemental analyses, IR and (1H, l3C, and 31P) NMR. The crystal structure of [S2POCMe2CMe2O]AuCl2, was determined. These new complexes have shown their growth inhibiting potential against various bacterial strains with moderate to good activity.

Long-chain alkyl esters of O,O-dialkyl dithiophosphoric and thionophosphoric acids prepared on the basis of red phosphorus, elemental sulfur, alcohols, and industrial fractions of higher monoolefins

Mixtures of long chain S-alkyl O,O-dialkyl dithiophosphates, and O-alkyl O,O-dialkyl thionophosphates were obtained by the reaction of red phosphorus with elemental sulfur, alcohols, and industrial fractions of C16-C18 and C20-C26 of higher olefins in the presence of Lewis acid catalysts. The products obtained possess high anticorrosion activities toward mild steel.

Z-Selective ring opening of vinyl oxetanes with dialkyl dithiophosphate nucleophiles

Dialkyl dithiophosphates selectively ring open vinyl oxetanes in excellent yields under mild reaction conditions to form useful allylic thiophosphate products with high Z-selectivity. The Royal Society of Chemistry 2013.

An efficient synthesis of O,O- di propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime and its analogues: A potential marine toxin

An efficient method for the synthesis of Ptychodiscus brevis toxin O,O- di n-propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime (TG-1) and its analogues has been developed using thermally stable and recyclable silica gel and Na2SO4 as a condensing agent and water scavenger, respectively. The compounds were evaluated against fish Rasbora daniconius by determining the LC50 and LC90 values. The results of biological evaluation showed that these compounds have high degree of toxicity. Copyright Taylor & Francis Group, LLC.

REACTIVITE DE L'ACIDE O,O'-DIISOPROPYLDITHIOPHOSPHORIQUE SUR DES ALCYNES VRAIS SULFURES

Reactivity of O,O'-diisopropyldithiophosphoric acid towards sulfurated monosubstituted alkynes.The reactivity of sulfurated monosubstituted alkynes with O,O'-diisopropyldithiophosphoric acid has been investigated, by three different methods (MeCN, Triton B, AIBN).Two types of alkenes were isolated.The selectivity of this reaction was studied. 13C and 31P NMR of these new sulfurated alkenes were reported. - Key words: O,O'-diisopropyldithiophosphoric acid, alkynes, sulfurated alkenes, 13C NMR, 31P NMR.

Reactivity of epichlorohydrin towards O,O'-dialkyldithiophosphoric acids

The selectivity of the reaction between O,O'-dialkyldithiophosphoric acids and epichlorohydrin is studied by two different methods.New phosphorus triesters are synthesized; they are potential lubricant additives. - Keywords: epichlorohydrin / O,O'-dialkyldithiophosphoric acid / lubricant additive / chlorohydrin

Multifunctional lubricant additives

Novel compounds of the formula (I) STR1 in which X is oxygen or sulfur, R and R1 independently of one another are C3 -C30 alkyl, R2 is C4 -C18 alkyl and R3, R4, R5 and R6 independently of one another are H, C1 -C20 alkyl, C3 -C20 alkenyl, benzyl, phenyl or phenyl which is substituted by C1 -C12 alkyl, and in which R5 and R6 can also be a direct bond, or R3 and R4 together are trimethylene, tetramethylene, STR2 and R5 and R6 are a direct bond or H, or in each case R3 and R6 together are a group =CH2 and R4 and R5 are H, or R4 and R5 together are a group =CH2 and R3 and R6 are H, or R3, R4, R5 and R6 together are STR3 and salts of these compounds, are described. They can be employed as multipurpose additives, in particular as anticorrosion, high pressure and antiwear additives, and as antioxidants in the lubricants and hydraulic or metalworking fluids.

Method of synethesizing sulfurized oligonucleotide analogs

A method for synthesizing sulfurized oligonucleotide analogs, such as phosphorothioate and phosphorodithioate analogs, is provided that employs a thiophosphorus compound, such as a thiophosphoric, dithiophosphoric, thiophosphinic, or dithiophosphinic acid disulfide or polysulfide, as a sulfurizing agent. The method of the invention may be used to sulfurize any phosphorous(III)-containing intermediate. Preferably, the method is practiced on a commercial DNA synthesizer using phosphoramidite and/or phosphorthioamidite intermediates.