611-62-1

Basic information

• Product Name: [1,1-Biphenyl]-2,4-diol
• Synonyms: [1,1-Biphenyl]-2,4-diol;4-(2-hydroxyphenyl)phenol
• CAS NO: 611-62-1
• Molecular Formula: C₁₂H₁₀O₂
• Molecular Weight: 186.2066
• Mol File: 611-62-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 162.5°C
• Boiling Point: 342°C (estimate)
• Appearance: /
• Density: 1.1032 (rough estimate)
• Refractive Index: 1.6086 (estimate)
• PKA: 10.00±0.35(Predicted)
• CAS DataBase Reference: [1,1-Biphenyl]-2,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1-Biphenyl]-2,4-diol(611-62-1)
• EPA Substance Registry System: [1,1-Biphenyl]-2,4-diol(611-62-1)

Safety Data

• Hazardous Substances Data: 611-62-1(Hazardous Substances Data)

Usage

General Description

[1,1-Biphenyl]-2,4-diol is a compound with the chemical formula C12H10O2 and is also known as 2,4-dihydroxy-1,1'-biphenyl. It is a derivative of biphenyl and contains two hydroxyl groups attached to the benzene rings. [1,1-Biphenyl]-2,4-diol is commonly used in the synthesis of pharmaceuticals and organic compounds. It is also used as a building block for the production of dyes, resins, and polymers. Additionally, [1,1-Biphenyl]-2,4-diol has antioxidant properties and has been studied for potential applications in skincare and cosmetic products. However, it is important to handle this compound with caution as it may cause skin and eye irritation and is toxic if ingested or inhaled in large quantities.

Upstream product

• 108-95-2 phenol 
• 56-23-5 tetrachloromethane 
• 7732-18-5 water 
• 106-48-9 4-chloro-phenol 
• 98-67-9 p-hydoroxybenzenesulfonic acid 
• 609-46-1 phenol-2-sulfonic acid 
• 533-58-4 2-Iodophenol 
• 93-99-2 benzoic acid phenyl ester 
• 65109-75-3 N-(phenoxy)-4-methylbenzenesulfonamide 
• 2122-46-5 phenoxy radical 

Downstream Products

• 35354-74-6 Honokiol 
• 120-80-9 benzene-1,2-diol 
• 123-31-9 hydroquinone 
• 106-51-4 p-benzoquinone 

Relevant articles and documents

Mechanism of 2-iodophenol photolysis in aqueous solution

The photolysis of 2-iodophenol (2-IPhOH) was investigated by means of laser flash photolysis and product studies. Two major heterolytic dehalogenation pathways could be evidenced upon irradiation of anionic 2-IPhO-: ring contraction leading to cyclopentadienic acids via a Wolff rearrangement (φa = 0.11 ± 0.02), and α-ketocarbene formation (φc = 0.03 ± 0.01) yielding products characteristic for triplet carbene reactivity. In contrast, the irradiation of neutral 2-IPhOH leads mainly to homolytic cleavage of the carbon-halogen bond (φ = 0.08 ± 0.01) with subsequent formation of biphenyls in deoxygenated solution. This specific reaction, which is not observed with other halogenated phenols, is explained by the low energy of the C-I bond. The relative efficiencies of the heterolytic pathways in the halogenophenol series are discussed in terms of the multiplicity of the excited states involved and of the internal heavy atom effect.

Products of oxidative coupllng of phenol by horseradish peroxidase

The oxidation and coupling of phenol by horseradish peroxidase in the presence of hydrogen peroxide yielded dimers trimers and higher molecular weight polymers which are mostly insoluble in water, so the products may be removed by centrifugation. However we discovered some products, such as dimers o,o'-biphenol, p,p'-biphenol, o,p'-biphenol, o-phenoxyphenol and p-phenoxyphenol, even though trimer 4-(4-phenoxyphenoxy)phenol were present in the aqueous phase at a very low concentration.

SECOND-ORDER COMBINATION REACTION OF PHENOXYL RADICALS

Phenoxy radicals, when produced pulse radiolytically at concentrations > 1E-4 M, combine in second-order processes to give 2,2'-, 2,4', and 4,4'-dihydroxybiphenyl as the predominant products.The ratios of these products observed under a variety of conditi