61451-78-3

Basic information

• Product Name: HMPPA
• Synonyms: HMPPA;Hydroxymethylphenylphosphinic acid;3-(4-Hydroxymethylphenoxy)propionic acid≥ 99% (HPLC)
• CAS NO: 61451-78-3
• Molecular Formula: C₇H₉O₃P
• Molecular Weight: 172.118321
• Mol File: 61451-78-3.mol

Chemical Properties

• Boiling Point: 445.008 °C at 760 mmHg
• Flash Point: 222.933 °C
• Appearance: /
• Density: 1.348 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.559
• Water Solubility: 1704g/L(34.29 oC)
• CAS DataBase Reference: HMPPA(CAS DataBase Reference)
• NIST Chemistry Reference: HMPPA(61451-78-3)
• EPA Substance Registry System: HMPPA(61451-78-3)

Safety Data

• Hazardous Substances Data: 61451-78-3(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

InChI:InChI=1/C7H9O3P/c8-6-11(9,10)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,9,10)

Upstream product

• 50-00-0 formaldehyd 
• 172487-18-2 ethyl Phenylphosphinate 
• 1779-48-2 phenylphosphinic acid 
• 591-50-4 iodobenzene 
• 653584-99-7 benzyloxymethyl-phenyl-phosphinic acid ethyl ester 

Downstream Products

• 64128-97-8 methyl hydroxymethanephenylphosphinate 
• 40561-09-9 phenyl(chloromethyl)phosphinic acid chloride 

Relevant articles and documents

Synthesis and structural characterization of a dimolybdenum complex bridged by the hydroxymethylphenylphosphinate ligand

Hydroxymethylphenylphosphinic acid, 1 was synthesized and structurally characterized by single crystal X-ray diffraction. Ligand 1 crystallized in the monoclinic P21 space group with two molecules comprising the unit cell and cell dimensions a

Synthesis, reactivity and stereochemistry of new phosphorus heterocycles with 5- or 6-membered rings

Syntheses of novel phosphorus heterocycles containing α-amino or α-hydroxyphosphonic or phosphinic acids motifs are developed. 2,3-dihydro-1,3-oxaphospholes (1) and 1,4,2-oxazaphosphinanes (2) exhibit a reactive part, respectively the enolether moiety and the P-H bond, which allows various structural modifications: (i) for 1a, by introduction of amino substituents, (ii) for 2a, by hydroxy- or aminoalkylation, by Michael addition or by P-arylation. These reactions present generally a good or even an excellent kinetic diastereoselectivity which can often be predicted by molecular models of the transition states.

Synthesis of New Arylhydroxymethylphosphinic Acids and Derivatives

The synthesis of a new series of arylhydroxymethylphosphinic acid derivatives is described. The protected compounds were prepared by a palladium(0) catalysed arylation of ethyl benzyloxymethylphosphinate with aryl halides. Subsequent hydrogenolysis of the

Process for the preparation of an oligomer flame-retarding additive and its use for endowing a linear polyester with self-extinguishing characteristics

An oligomer flame-retarding additive can be defined by the general formula wherein:, R is the hydrogen atom, or a linear or branched alkyl radical, containing from 1 to 6 carbon atoms;, mtakes the value 1, 2 or 3;, ntakes a value, or an average value, comprised within the range of from 2 to 50. Such an additive is obtained by means of the oligomerization of a hydroxyalkylenephenylphosphinic acid or of a related alkyl ester thereof. According to another form of practical embodiment, the flame-retarding additive is the product of co-oligomerization of a hydroxyalkylenephenylphosphinic acid, or of a related alkyl ester thereof, with a phenylphosphonic acid or a related alkyl ester thereof. Such oligomer additives are used for endowing a linear polyester with self-extinguishing characteristics.