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CAS

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Chloromethyl isobutyrate, a member of the ester class, is a colorless liquid with a pungent odor. It serves as a versatile chemical intermediate in the synthesis of various organic compounds and is utilized as a solvent in chemical reactions. Due to its reactivity and potential hazards, it requires careful handling to prevent irritation to the skin, eyes, and respiratory system, as well as to avoid vigorous reactions with oxidizing agents and flammability risks.

61644-18-6

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61644-18-6 Usage

Uses

Used in Chemical Synthesis:
Chloromethyl isobutyrate is used as a chemical intermediate for the production of various organic compounds, contributing to the synthesis of a wide range of chemical products.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, chloromethyl isobutyrate is used as a raw material in the manufacturing process, playing a crucial role in the development of medicinal compounds.
Used in Agricultural Product Production:
Chloromethyl isobutyrate is also utilized in the production of agricultural products, where it may contribute to the formulation of agrochemicals or other related substances.
Used as a Solvent in Chemical Reactions:
Due to its solvent properties, chloromethyl isobutyrate is employed in various chemical reactions to facilitate processes and improve the efficiency of synthesis.
Safety Precautions:
Given its hazardous nature, chloromethyl isobutyrate should be handled with care to minimize the risk of skin, eye, and respiratory irritation. It is essential to avoid contact with oxidizing agents and to manage its flammability to ensure safe usage in industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 61644-18-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,6,4 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 61644-18:
(7*6)+(6*1)+(5*6)+(4*4)+(3*4)+(2*1)+(1*8)=116
116 % 10 = 6
So 61644-18-6 is a valid CAS Registry Number.

61644-18-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name chloromethyl 2-methylpropanoate

1.2 Other means of identification

Product number -
Other names Chloromethyl 2-methylpropionate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61644-18-6 SDS

61644-18-6Relevant articles and documents

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

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Page/Page column 80; 81, (2019/07/20)

The present invention provides a compound of formula (II): an inhibitor of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases. Its prodrugs are disclosed.

COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY

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Page/Page column 13-14, (2019/11/12)

The present invention relates to compound of Formula I or a pharmaceutically acceptable salt thereof (Formula I) wherein R1 is Formula (AA) or Formula (BB) where the squiggly line indicates the point of attachment to the rest of the molecule; R2 is F or Formula (CC) where the squiggly line indicates the point of attachment to the rest of the molecule; R3 is H or CH3; Z is O or is absent; and R4 is -OC1-3alkyl, C1-30alkyl, or -N(CH3)2.

NMDA ANTAGONIST PRODRUGS

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Paragraph 0081-0083, (2018/04/17)

Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, useful for the treatment of depression (particularly major depressive disorder) or pain; compositions comprising them, and methods of making them.

Substituted aza indole compounds and salts thereof, composition and use thereof

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Paragraph 0377; 0378; 0384; 0386; 0387, (2018/11/03)

The invention provides a substituted azaindole compound having a structure as represented by a formula (I) and a pharmaceutically acceptable salt and a medicinal preparation thereof. The compound is used for adjusting activity of protein kinase and adjusting intercellular or intracellular signal response. The invention further relates to a pharmaceutical composition including the compound and a method of applying the pharmaceutical composition to treatment of highly proliferative diseases of mammals, especially of mankind.

NMDA ANTAGONIST PRODRUGS

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Paragraph 00072; 00073; 00074, (2015/05/26)

Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, useful for the treatment of depression (particularly major depressive disorder) or pain; compositions comprising them, and methods of making them.

SUBSTITUTED AZAINDOLE COMPOUNDS, SALTS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF USE

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Paragraph 0289-0290; 0294-0296, (2014/03/24)

The present invention provides substituted azaindole prodrugs, methods of making said prodrugs, pharmaceutical compositions of said prodrugs and methods of using said prodrugs and pharmaceutical compositions thereof to treat or prevent diseases or disorders such as cancer.

NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES

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Page/Page column, (2014/04/18)

Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.

COMPOUNDS AND THERAPEUTIC USES THEREOF

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Paragraph 00310-00311; 00322, (2014/01/17)

The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.

4-SUBSTITUTED-3-PHENYLSULFANYLMETHYL-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS

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Page/Page column 12, (2012/06/01)

A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.

SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS

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Page/Page column 88, (2012/10/18)

The present invention relates to the synthesis and application of novel chiral/ achiral substituted methyl formyl reagents to modify pharmaceutical agents and/or biologically active substances to modify the physicochemical, biological and/or pharmacokinetic properties of the resulting compounds from the unmodified original agent.

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