6305-43-7Relevant articles and documents
A new colorimetric and fluorescent chemosensor based on thiazolyl-hydrazone for sensitive detection of copper ions
Jia, Zhaodong,Wei, Jingna,Ren, Yaping,Zhang, Ning,Hao, Xin-Qi,Zhu, Xinju,Xu, Yan
, p. 609 - 614 (2020)
Abstract: A Cu2+-specific chemosensor probe thiazolyl-hydrazone (BL) has been designed and prepared, which provide tridentate chelate NNO coordination mode for Cu2+ with binding stoichiometry of 1:1. The BL solution exhibits a rapid color change from colorless to yellow along with a new intense absorption band at 414?nm upon binding to Cu2+ cation, whereas other metal cations do not induce such a change. The analytical detection limit is 0.75?μM, and the naked eye detection limit is as low as 20?μM. Additionally, the emission signal of BL could be quenched by Cu2+ and Fe3+ with a detection limit of 7.2?μM and 4.3?μM, respectively. Graphic abstract: [Figure not available: see fulltext.].
Benzimidazolium salts with 1,4-dihydro-naphtho[1,8-ef]-1,4-diazepine: Synthesis, structure and recognition for copper(II) ion
Liu, Qingxiang,Huo, Ran,Wei, Dengche,Zhao, Xiaojun,Zhao, Zhixiang,Cai, Kangqing
, p. 1 - 6 (2017)
Two new benzimidazolium salts with the same cationic moiety and different anionic moieties 2-[2′-(N-benzyl-benzimidazoliumyl)]-1,4-dihydro-naphtho[1,8-ef]-1,4-diazepine bromide (1) and 2-[2′-(N-benzyl-benzimidazoliumyl)]-1,4-dihydro-naphtho[1,8-ef]-1,4-diazepine hexafluorophosphate (2) were prepared and characterized. The structure of 1 was determined by X-ray single crystal diffraction and 1H NMR and 13C NMR spectroscopy. Selective recognition of 2 for cations (Li+, Na+, K+, NH4+, Ag+, Ca2+, Co2+, Ni2+, Cu2+, Zn2+, Cr3+, Cd2+, Al3+, Pb2+, Hg+ and Hg2+, and use of their nitrate salts) was investigated by fluorescence and UV/vis titrations in C2H5OH/H2O (v:v?=?1:1) at 25?°C. The response of 2 to Cu2+ can be observed through both remarkable fluorescence enhancement and color change under sunlight (from yellow to red). The results indicated that 2 can distinguish Cu2+ from other cations via the instrument and naked eyes, and this is greatly convenient in practical operation.
Synthesis method of 3,3,4,4-tetrafluoropyrrolidine
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Paragraph 0014; 0015; 0019; 0020; 0024; 0025, (2018/04/21)
The invention discloses a synthesis method of 3,3,4,4-tetrafluoropyrrolidine and mainly solves the technical problems of poisonous introduced fluorine, relatively long steps and relatively low yield in the existing synthesis process. The synthesis method disclosed by the invention comprises four steps: firstly, mixing butanedione with chloroform, then, carrying out addition on the mixture and bromine to form 1,4-dibromo-2,3-butanedione; secondly, introducing sulfur tetrafluoride into the obtained 1,4-dibromo-2,3-butanedione, and carrying out a reaction to obtain 1,4-dibromo-2,2,3,3-tetrafluorobutane; thirdly, carrying out a high-temperature reaction on 1,4-dibromo-2,2,3,3-tetrafluorobutane and benzylamine to obtain 1-benzyl-3,3,4,4-tetrafluoropyrrolidine hydrochloride; and fourthly, carrying out catalytic hydrogenation debenzylation on 1-benzyl-3,3,4,4-tetrafluoropyrrolidine hydrochloride to obtain 3,3,4,4-tetrafluoropyrrolidine. The invention provides the synthesis method of 3,3,4,4-tetrafluoropyrrolidine which is relatively low in toxicity, low in raw material price, simple in operation and high in yield.