64001-06-5

Basic information

• Product Name: 4-[(tetrahydro-2-furanyl)oxy]-1-butanol
• Synonyms: 4-[(tetrahydro-2-furanyl)oxy]-1-butanol;1-Butanol, 4-[(tetrahydro-2-furanyl)oxy]-;2-(4-Hydroxybutoxy)tetrahydrofuran;4-[(TETRAHYDRO-FURAN-2-YL)OXY]-1-BUTANOL;4-((Tetrahydrofuran-2-yl)oxy)butan-1-ol
• CAS NO: 64001-06-5
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.21
• Product Categories: Heterocycles;Impurities;Intermediates
• Mol File: 64001-06-5.mol

Chemical Properties

• Boiling Point: 260.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: 4-[(tetrahydro-2-furanyl)oxy]-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(tetrahydro-2-furanyl)oxy]-1-butanol(64001-06-5)
• EPA Substance Registry System: 4-[(tetrahydro-2-furanyl)oxy]-1-butanol(64001-06-5)

Safety Data

• Hazardous Substances Data: 64001-06-5(Hazardous Substances Data)

Usage

Uses

2-(4-Hydroxybutoxy)tetrahydrofuran is an impurity of Poly(butylene terephthalate) and a by-product of 1,4-Butanediol.

Upstream product

• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 1191-99-7 2,3-dihydro-2H-furan 
• 110-63-4 Butane-1,4-diol 

Downstream Products

• 76702-30-2 1,4-bis(tetrahydro-2-furyloxy)butane 

Relevant articles and documents

PROTECTIVE GROUP, ORGANIC SYNTHESIS METHOD, PROTECTIVE GROUP INTRODUCTION METHOD AND PROTECTOR

PROBLEM TO BE SOLVED: To provide a protective group which inhibits the dissolution of a protector in a water layer side and allows protectors to be obtained with good yields. SOLUTION: This invention relates to a protective group of a functional group used for an organic synthesis method, the protective group represented by general formula (1), an organic synthesis method using the protective group, a protective group introduction method and a protector. (In the general formula (1), R1 to R7 independently represent a hydrogen atom or an alkyl group having 5 or less carbon atoms, and at least one of R1 to R7 represents an alkyl group having 5 or less carbon atoms.) COPYRIGHT: (C)2015,JPOandINPIT

Method for producing 1,4-butanediol

A process for preparing 1,4-butanediol and, if desired, gamma-butyrolactone and THF by oxidizing butane or benzene to form a product stream including maleic anhydride, absorbing maleic anhydride from the product stream with a high-boiling inert solvent in an absorption stage to give a liquid absorption product, esterifying the liquid absorption product with a C1-C5 esterifying alcohol in an esterification stage to form an esterification product comprising the corresponding diester and high-boiling inert solvent, then hydrogenating the esterification product to give a hydrogenation product which comprises the products of value, 1,4-butanediol and, if desired, gamma-butyrolactone and tetrahydrofuran and the esterifying alcohol and which is separated by distillation into the products of value and the esterifying alcohol, and recycling the esterifying alcohol to the esterification zone, which comprises separating the esterification product into the diester and the inert solvent by distillation under reduced pressure prior to the hydrogenation, recycling the inert solvent to the absorption stage, and hydrogenating the diester in the liquid phase over a fixed-bed catalyst.