644984-78-1

Basic information

• Product Name: Benzoic acid, 4-bromo-2-ethyl- (9CI)
• Synonyms: Benzoic acid, 4-bromo-2-ethyl- (9CI);4-Bromo-2-ethylbenzoic acid
• CAS NO: 644984-78-1
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07056
• Product Categories: ETHYL
• Mol File: 644984-78-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-bromo-2-ethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-bromo-2-ethyl- (9CI)(644984-78-1)
• EPA Substance Registry System: Benzoic acid, 4-bromo-2-ethyl- (9CI)(644984-78-1)

Safety Data

• Hazardous Substances Data: 644984-78-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 4-bromo-2-ethyl(9CI) is used as an intermediate in the synthesis of various pharmaceutical compounds for its enhanced reactivity and solubility.
Used in Cosmetics Industry:
Benzoic acid, 4-bromo-2-ethyl(9CI) is used as a preservative in cosmetics due to its potential antimicrobial and antifungal properties.
Used in Food Industry:
Benzoic acid, 4-bromo-2-ethyl(9CI) is used as a food preservative to extend the shelf life of various food products.
Used in Chemical Synthesis:
Benzoic acid, 4-bromo-2-ethyl(9CI) is used as a building block in the synthesis of other organic compounds due to its enhanced reactivity.

Upstream product

• 586-76-5 4-Bromobenzoic acid 
• 38227-87-1 2,2,6,6-tetramethylpiperidinyl-lithium 
• 74-88-4 methyl iodide 
• 925-90-6 ethylmagnesium bromide 
• 112704-79-7 2-fluoro-4-bromobenzoic acid 
• 68837-59-2 4-bromo-2-methylbenzoic acid 

Downstream Products

• 345965-25-5 isopropyl 2-ethyl-4-bromobenzoate 
• 552330-86-6 5-bromoisoindolin-1-one 
• 194487-79-1 methyl 4-bromo-2-ethylbenzoate 
• 877131-20-9 2-(4-bromo-2-ethylphenyl)acetonitrile 
• 855931-72-5 2-(4-bromo-2-ethylphenyl)acetic acid 
• 1227090-87-0 methyl 2-(4-bromo-2-ethylphenyl)acetate 
• 877131-77-6 2-(4-bromo-2-ethylbenzyl)isoindoline-1,3-dione 
• 935260-96-1 methyl 4-cyano-2-ethylbenzoate 
• 741698-83-9 4-bromo-2-isopropylbenzoic acid 
• 1416979-60-6 Ethyl 4-bromo-2-ethylbenzoate 
• 1160707-43-6 4-bromo-2-ethyl-benzoyl chloride 

Relevant articles and documents

Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases

Autoreactive B cell-derived antibodies form immune complexes that likely play a pathogenic role in autoimmune diseases. In systemic lupus erythematosus (SLE), these antibodies bind Fc receptors on myeloid cells and induce proinflammatory cytokine producti

BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to benzofurane and benzothiophene derivatives of formula (I) Formula (I) wherein (R1)n, R2, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to phenyl derivatives of formula (I) Formula (I) wherein (R1)n, R3, R4a, R4b, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (III) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS

The invention relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): (I), wherein L1, A, X1, X2, R1, R2, and R3 are described herein.

ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Provided are compounds of Formula I as JAK inhibitors, which are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS

The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.

Pesticidal compositions and processes related thereto

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (“Formula One”).