552330-86-6

Basic information

• Product Name: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE
• Synonyms: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE;5-BroMo-1-isoindolinone, 96%;5-BroMo-2,3-dihydro-1H-isoindol-1-one;4-BroMo-2,3-dihydroisoindol-1-one;5-BroMo-1-oxo-isoindoline;1H-Isoindol-1-one, 5-broMo-2,3-dihydro-;5-Bromo-2,3-dihydro-1-oxo-1H-isoindole;5-Bromoisoindolin-1-one≥ 98%(GC)
• CAS NO: 552330-86-6
• Molecular Formula: C₈H₆BrNO
• Molecular Weight: 212.05
• Mol File: 552330-86-6.mol
• Article Data: 24

Chemical Properties

• Melting Point: 267 °C
• Boiling Point: 448.367 °C at 760 mmHg
• Flash Point: 224.965 °C
• Appearance: /
• Density: 1.666 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.75±0.20(Predicted)
• CAS DataBase Reference: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE(552330-86-6)
• EPA Substance Registry System: 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE(552330-86-6)

Safety Data

• Hazardous Substances Data: 552330-86-6(Hazardous Substances Data)

Usage

Chemical Properties

Pink Solid

InChI:InChI=1/C8H6BrNO/c9-6-1-2-7-5(3-6)4-10-8(7)11/h1-3H,4H2,(H,10,11)

Upstream product

• 78471-43-9 methyl 4-bromo-2-(bromomethyl)benzoate 
• 194487-79-1 methyl 4-bromo-2-ethylbenzoate 
• 644984-78-1 4-bromo-2-ethylbenzoic acid 
• 201230-82-2 carbon monoxide 
• 10269-01-9 3-bromobenzylamine 
• 1972-28-7 diethylazodicarboxylate 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 68837-59-2 4-bromo-2-methylbenzoic acid 

Downstream Products

• 926307-72-4 methyl 1-oxo-2,3-dihydro-1H-isoindole-5-carboxylate 
• 1613639-03-4 2-[5-(1-oxo-2,3-dihydro-1H-isoindol-5-yl)pyridin-3-ylamino]-2-phenylacetamide 
• 1567837-01-7 2,4-difluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzamide 
• 1567836-94-5 5-(5-(3-aminophenyl)thiophen-2-yl)-2-methylisoindolin-1-one 
• 1567837-79-9 4-fluoro-N-((5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)carbamothioyl)benzamide 
• 1567836-38-7 2,4-difluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 
• 868066-91-5 5-bromo-2-methyl-1,3-dihydroisoindol-1-one 
• 1357104-66-5 C₃₆H₄₄N₂O₅ 
• 1357104-60-9 C₃₇H₄₆N₂O₅ 
• 1357104-53-0 C₁₀H₇F₃N₂O₂ 
• 1357104-52-9 C₁₅H₁₄N₂O 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase

Aberrant activity of the histone methyltransferase polycomb repressive complex 2 (PRC2) has been linked to several cancers, with small-molecule inhibitors of the catalytic subunit of the PRC2 enhancer of zeste homologue 2 (EZH2) being recently approved fo

Degradable hydrogel under physiological conditions

The present invention discloses a hydrogel that can be degraded under physiological conditions. The hydrogel includes at least one backbone moiety and an optional crosslinking moiety, and biodegradable linkers connecting backbone moieties and crosslinking moieties can be degraded by intramolecular cyclization.