194487-79-1

Basic information

• Product Name: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester
• Synonyms: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester;4-Bromo-2-ethyl-benzoic acid methyl ester;Methyl 4-bromo-2-ethylbenzoate
• CAS NO: 194487-79-1
• Molecular Formula: C₁₀H₁₁BrO₂
• Molecular Weight: 258.11178
• Mol File: 194487-79-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(194487-79-1)
• EPA Substance Registry System: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(194487-79-1)

Safety Data

• Hazardous Substances Data: 194487-79-1(Hazardous Substances Data)

Usage

General Description

(S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester is a chemical compound with the molecular formula C11H13BrNO2. It is a methyl ester derivative of 2-(1-amino-ethyl)-4-bromo-benzoic acid, which makes it a potential intermediate for the synthesis of pharmaceuticals and other organic compounds. (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester is a white to off-white solid that is soluble in organic solvents and has a melting point of around 70-80 degrees Celsius. It is commonly used in chemical research and drug development due to its potential pharmacological properties and applications in organic synthesis. However, further research and testing are needed to fully understand its uses and potential benefits.

Upstream product

• 67-56-1 methanol 
• 2386-64-3 ethylmagnesium chloride 
• 112704-79-7 2-fluoro-4-bromobenzoic acid 
• 644984-78-1 4-bromo-2-ethylbenzoic acid 
• 74-88-4 methyl iodide 
• 68837-59-2 4-bromo-2-methylbenzoic acid 

Downstream Products

• 935260-96-1 methyl 4-cyano-2-ethylbenzoate 
• 1227090-87-0 methyl 2-(4-bromo-2-ethylphenyl)acetate 
• 855931-72-5 2-(4-bromo-2-ethylphenyl)acetic acid 
• 877131-20-9 2-(4-bromo-2-ethylphenyl)acetonitrile 
• 877131-21-0 (4-bromo-2-ethylphenyl)methanol 
• 552330-86-6 5-bromoisoindolin-1-one 

Relevant articles and documents

MACROCYCLIC COMPOUND AND USE THEREOF

A compound represented by the following formula (I): wherein each symbol in the formula is as described herein or a salt thereof has an NRF2 activating activity, and is expected to be useful as a preventive or therapeutic agent for diseases associated with oxidative stress, in particular, hepatic disease (for example, non-alcoholic steatohepatitis (NASH)), cardiovascular disease (for example, heart failure or pulmonary arterial hypertension), lung disease (for example, chronic obstructive pulmonary disease (COPD)), kidney disease (for example, chronic kidney disease (CKD) or acute kidney injury (AKI)), central nervous system disease (for example, Parkinson's disease), mitochondrial disease (for example, Friedreich motor ataxia, mitochondrial myopathy), inflammatory disease (for example, multiple sclerosis (MS), inflammatory bowel disease (IBD)), sickle cell disease, cancer, or the like.

PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

HISTONE DEMETHYLASE INHIBITORS

Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.