683-19-2Relevant articles and documents
Peppard et al.
, p. 2065 (1965)
Selective Substitution of POCl 3 with Organometallic Reagents: Synthesis of Phosphinates and Phosphonates
Verbelen, Bram,Dehaen, Wim,Binnemans, Koen
, p. 2019 - 2026 (2018/04/14)
The selectivity of the substitution reaction of phosphoryl chloride with organometallic reagents was investigated using NMR spectroscopy. This led to the discovery that the selectivity of the substitution reaction can be tuned by choosing a proper organometallic reagent. A phosphinate could be obtained by using a Grignard reagent whereas an organozinc reagent provided a phosphonate. Based on these results, one-pot synthetic methods for the preparation of phosphinates and phosphonates using commercially available starting materials were developed. Both methods allow the synthesis of a broad range of either phosphinate or phosphonate derivatives in a straightforward and general procedure. Moreover, using these one-pot procedures, mixed systems substituted with different alkyl/aryl groups can be prepared.
Microwave-assisted synthesis of dialkylphosphinic acids and a structure-reactivity study in rare earth metal extraction
Du, Ruo-Bing,An, Huaying,Zhang, Suhui,Yu, Donghai,Xiao, Ji-Chang
, p. 104258 - 104262 (2015/12/24)
Dialkylphosphinic acids were synthesised by a microwave-assisted method with high yields and wide substrate applicability. A structure-reactivity study indicates that an increase in steric hindrance in the β position led to a decrease of extraction ratio and heavy rare earth element separation activity. A computational study was also conducted to understand the steric effect.
Synthesis of disubstituted phosphinates via palladium-catalyzed hydrophosphinylation of H-phosphinic acids
Petit, Christelle,Fecourt, Fabien,Montchamp, Jean-Luc
, p. 1883 - 1888 (2011/10/04)
The first metal-catalyzed hydrophosphinylation of unsaturated hydrocarbons with H-phosphinic acids is described. A strategy to activate the P-H bond through control of the tautomeric equilibrium using ethylene glycol is described. The reactions also avoid chromatographic purification. Copyright