6837-99-6 Usage
Uses
Used in Pharmaceutical Industry:
3-AMINO-N-BUTYLBENZAMIDE is used as a potential PARP inhibitor for its role in cancer treatment. It targets the enzyme poly(ADP-ribose) polymerase, which is involved in DNA repair mechanisms, making it a candidate for treating cancers that rely on these mechanisms for survival and proliferation.
Used in Cancer Treatment:
3-AMINO-N-BUTYLBENZAMIDE is utilized as an anticancer agent, particularly for cancers that have defects in DNA repair pathways. Its inhibition of PARP can lead to the accumulation of DNA damage in cancer cells, ultimately resulting in cell death. This makes it a valuable tool in the development of targeted therapies for specific cancer types.
Used in Neuroprotection and Anti-Inflammatory Research:
3-AMINO-N-BUTYLBENZAMIDE is employed as a compound of interest in neuroprotective and anti-inflammatory studies. Its potential to protect neurons and reduce inflammation makes it a candidate for the treatment of neurodegenerative diseases and conditions involving inflammation in the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 6837-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6837-99:
(6*6)+(5*8)+(4*3)+(3*7)+(2*9)+(1*9)=136
136 % 10 = 6
So 6837-99-6 is a valid CAS Registry Number.
6837-99-6Relevant academic research and scientific papers
3-(2′-Bromopropionylamino)-benzamides as novel S-phase arrest agents
Hu, Laixing,Li, Zhuo-rong,Li, Jian-Nong,Qu, Jinrong,Jiang, Jian-Dong,Boykin, David W.
, p. 6847 - 6852 (2008/09/16)
We report the synthesis, antiproliferative activity, and SAR of novel 3-(2′-bromopropionylamino)-benzamides. Many of the benzamide compounds showed potent cytotoxicities against Molt-3 leukemia cells. Several compounds exihibited cytotoxicities (under 6.5
Thermosensitive recording material and novel color developer compounds
-
, (2008/06/13)
Disclosed is a thermosensitive recording material comprising a sheet-shaped support and a thermosensitive recording layer which is formed on at least one surface of the support and comprises a colorless or light-colored dye precursor and a color developer capable of reacting with the dye precursor and inducing color formation therein upon application of heat thereto, the color developer comprising a compound represented by the following formula (I) or analog thereof:: The thermosensitive recording material has high sensitivity and can prevent white background portions from coloring and recorded images from decolorizing in an environmental resistance test.