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D(-)Prolinol, also known as (R)-(-)-2-Pyrrolidinemethanol or D-prolinol, is a chiral secondary amino alcohol that serves as a key scaffold in the development of potent Growth Hormone Secretagogue receptor (GHSR) agonists. Its (R)-configuration, particularly the α-methyl stereochemistry, plays a critical role in enhancing GHSR activity, as demonstrated in the optimization of lead compounds with nanomolar potency. D(-)Prolinol's structural versatility allows for derivatization into pharmacologically active molecules, making it valuable for potential therapeutic applications in growth hormone-related disorders, metabolic conditions, and muscle-wasting diseases.

68832-13-3

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68832-13-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 68832-13-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,8,3 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68832-13:
(7*6)+(6*8)+(5*8)+(4*3)+(3*2)+(2*1)+(1*3)=153
153 % 10 = 3
So 68832-13-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H11NO/c7-4-5-2-1-3-6-5/h5-7H,1-4H2/p+1/t5-/m1/s1

68832-13-3 Well-known Company Product Price

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  • TCI America

  • (P1274)  D-Prolinol  >99.0%(GC)(T)

  • 68832-13-3

  • 1g

  • 590.00CNY

  • Detail
  • TCI America

  • (P1274)  D-Prolinol  >99.0%(GC)(T)

  • 68832-13-3

  • 5g

  • 1,750.00CNY

  • Detail
  • TCI America

  • (P1274)  D-Prolinol  >99.0%(GC)(T)

  • 68832-13-3

  • 25g

  • 5,500.00CNY

  • Detail
  • Alfa Aesar

  • (L11109)  (R)-(-)-Prolinol, 98+%   

  • 68832-13-3

  • 250mg

  • 183.0CNY

  • Detail
  • Alfa Aesar

  • (L11109)  (R)-(-)-Prolinol, 98+%   

  • 68832-13-3

  • 1g

  • 682.0CNY

  • Detail
  • Alfa Aesar

  • (L11109)  (R)-(-)-Prolinol, 98+%   

  • 68832-13-3

  • 5g

  • 2971.0CNY

  • Detail
  • Alfa Aesar

  • (L11109)  (R)-(-)-Prolinol, 98+%   

  • 68832-13-3

  • 25g

  • 13041.0CNY

  • Detail
  • Aldrich

  • (281697)  (R)-(−)-2-Pyrrolidinemethanol  99%

  • 68832-13-3

  • 281697-1G

  • 747.63CNY

  • Detail
  • Aldrich

  • (281697)  (R)-(−)-2-Pyrrolidinemethanol  99%

  • 68832-13-3

  • 281697-5G

  • 3,387.15CNY

  • Detail

68832-13-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name D-prolinol

1.2 Other means of identification

Product number -
Other names H-D-PROLINOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:68832-13-3 SDS

68832-13-3Upstream product

68832-13-3Relevant articles and documents

Ochraceopetalin, a mixed-biogenetic salt of polyketide and amino acid origins from a marine-derived aspergillus ochraceopetaliformis fungus

Park, Sung Chul,Lee, Jung-Ho,Hwang, Ji-Yeon,Kwon, Oh-Seok,Liao, Lijuan,Oh, Dong-Chan,Oh, Ki-Bong,Shin, Jongheon

, (2021/08/16)

Ochraceopetalin (1), a mixed-biogenetic salt compound and its component 2 were isolated from the culture broths of a marine-derived fungus, Aspergillus ochraceopetaliformis. Based on combined spectroscopic and chemical analyses, the structure of 1 was determined to be a sulfonated diphenylether-aminol-amino acid ester guanidinium salt of an unprecedented structural class, while 2 was determined to be the corresponding sulfonated diphenylether. Ochraceopetaguanidine (3), the other guanidine-bearing aminol amino acid ester component, was also prepared and structurally elucidated. Compound 1 exhibited significant cytotoxicity against K562 and A549 cells.

Tolyprolinol, a new dipeptide from Tolypocladium sp. FKI-7981

Fukasawa, Wataru,Mori, Natsuki,Iwatsuki, Masato,Hokari, Rei,Ishiyama, Aki,Nakajima, Moe,Ouchi, Takahito,Nonaka, Kenichi,Kojima, Hiroki,Matsuo, Hirotaka,ōmura, Satoshi,Shiomi, Kazuro

, p. 682 - 684 (2018/03/26)

A new dipeptide, named tolyprolinol, was isolated from the static culture of a fungus, Tolypocladium sp. FKI-7981. The structure of tolyprolinol was elucidated as N-acetyl-l-phenylalanyl-l-prolinol. It showed moderate antimalarial activity but did not show cytotoxicity or any other antimicrobial property.

OPTISCH AKTIVE β(AMINO)ETHYL-PHOSPHONSAEUREESTER, β(AMINO)ETHYL-PHENYLPHOSPHINSAEUREESTER, β(AMINO)ETHYL-DIPHENYLPHOSPHINOXYDE UND β(AMINO)ETHYL-DIPHENYLPHOSPHINE

Maerkl, G.,Merkl, B.

, p. 4459 - 4462 (2007/10/02)

The title compounds are prepared by Michael-type additions of primary and secondary amines to P(O)-activated vinylsystems resp. diphenyl-vinylphosphine.

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