71-33-0

Basic information

• Product Name: 5-AZAURACIL
• Synonyms: 1,3,5-TRIAZINE-2,4(3H,5H)-DIONE;5-AZAURACIL;5-AZA-2,4-DIHYDROXYPYRIMIDINE;AZAURACIL, 5-;Allantoxaidin;Allantoxaidine;Oxaidin;s-Triazine-2,4(1H,3H)-dione
• CAS NO: 71-33-0
• Molecular Formula: C₃H₃N₃O₂
• Molecular Weight: 113.07
• EINECS: 200-750-0
• Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;All Inhibitors;Bases & Related Reagents;Inhibitors;Nucleotides;Heterocycles
• Mol File: 71-33-0.mol

Chemical Properties

• Melting Point: 281-282°C
• Boiling Point: 573.9 °C at 760 mmHg
• Flash Point: 300.9 °C
• Appearance: Crystalline Solid
• Density: 1.86 g/cm³
• Vapor Pressure: 9.02E-14mmHg at 25°C
• Refractive Index: 1.748
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Sparingly), Water (Slightly)
• PKA: 6.00±0.70(Predicted)
• CAS DataBase Reference: 5-AZAURACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AZAURACIL(71-33-0)
• EPA Substance Registry System: 5-AZAURACIL(71-33-0)

Safety Data

• Hazardous Substances Data: 71-33-0(Hazardous Substances Data)

Usage

Chemical Properties

Crystalline Solid

Uses

5-Azauracil is an antimetabolite

InChI:InChI=1/C3H3N3O2/c7-2-4-1-5-3(8)6-2/h1H,(H2,4,5,6,7,8)

Upstream product

• 1898-72-2 2,6-dimethoxy-1,3,5-triazine 
• 122-51-0 orthoformic acid triethyl ester 
• 57-13-6 urea 
• 27738-96-1 chlorocarbonyl isocyanate 

Downstream Products

• 873-48-3 1-Methyl-5-aza-uracil 
• 27032-78-6 2,4-dioxohexahydro-1,3,5-triazine 
• 108-19-0 BIURET 
• 61466-03-3 4,4-methine-bis-(3-methyl-1-phenyl-2-pyrazolin-5-one) 
• 58376-76-4 2,5,2',5'-tetraphenyl-1,2,2',4'-tetrahydro-4,4'-methanylylidene-bis-pyrazol-3-one 
• 61466-03-3 5-methyl-4-[(5-methyl-3-oxo-2-phenyl-2,4-dihydro-3H-pyrazol-4-yl)methylene]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 
• 234772-19-1 6-(4-bromophenyl)-[1,3,5]triazinan-2,4-dione 
• 1222100-21-1 6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazinan-2,4-dione 
• 61851-93-2 6-(4-dimethylaminophenyl)-[1,3,5]triazinan-2,4-dione 
• 61851-92-1 6-(4-chlorophenyl)-2,4-dioxo-1,3,5-triazinane 
• 1222100-22-2 6-(2,4,6-trimethyl-phenyl)-[1,3,5]triazinan-2,4-dione 

Relevant articles and documents

Chemoselective Demethylation of Methoxypyridine

A chemoselective demethylation method for various methoxypyridine derivatives has been developed. Treatment of 4-methoxypyridine with L-selectride in THF for 2 h at reflux temperature afforded 4-hydroxypyridine in good yield; no reaction to anisole occurred. The utility of our method was demonstrated by the efficient synthesis of the metabolic substances of the antiulcer agent omeprazole. Chemoselective demethylation at the site of 3,5-dimethyl-4-methoxypyridine in the presence of 4-methoxybenzimidazole was achieved.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof

The present invention relates to substituted 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine compounds of formula (I) having pharmacological activity, to solid phase synthesis methods for their preparation, to combinatorial libraries thereof, utilizing libraries of the compounds for drug discovery, and to pharmaceutical compositions thereof.

CHEMICAL COMPOUNDS

Triazine derivatives of formula (I) or salts thereof, wherein R1 represents a halogen atom or a group selected from hydroxy; C1-8 alkyl C1-6 alkoxy; C1-3 alkoxy C1-3 alkoxy; phenoxy or phenyl C1-3 alkoxy, wherein the phenyl group is optionally substituted by a halogen atom or a group selected from C1-3 alkyl, C1.3 alkoxy, or hydroxy; fluoro C1-3 alkyl; cyano; -CO2R3, wherein R3 represents a hydrogen atom or a C1-4 alkyl group; - CONR4R5, wherein R4 and R5 each independently represents a hydrogen atom or a C1-4 alkyl group, or, together with the nitrogen atom to which they are attached, form a saturated 5- to 7- membered ring, which ring optionally contains one or more atoms selected from an oxygen or a sulphur atom, or a group selected from -NH- or -N(CH3)-; and R2 represents a hydrogen or halogen atom, or a group selected from hydroxy, C1-6 alkyl or C1-6 alkoxy; are inhibitors of the enzyme 5-lipoxygenase. Processes for preparing the triazine derivatives of formula (I) and compositions containing them are also described

Triazinediones

Herbicidal and fungicidal triazinediones of the formula: STR1 wherein R1 is an aliphatic radical, R2 is a carboxylic acyl radical, R3 is a hydrogen atom or an aliphatic radical, and X is a hydrogen atom or an aliphatic radical.