7113-12-4

Basic information

• Product Name: 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE
• Synonyms: 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE
• CAS NO: 7113-12-4
• Molecular Formula: C₁₀H₉N₃OS
• Molecular Weight: 219.26
• Mol File: 7113-12-4.mol

Chemical Properties

• Melting Point: 136-138°C
• Appearance: /
• Density: 1.329g/cm³
• Refractive Index: 1.645
• CAS DataBase Reference: 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE(7113-12-4)
• EPA Substance Registry System: 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE(7113-12-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 7113-12-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE is used as a reagent in organic synthesis for its ability to facilitate the creation of complex organic molecules, which are essential in the development of new pharmaceutical drugs.
Used in Chemical Industry:
In the chemical industry, 2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE is utilized as a building block for the production of other chemical compounds, contributing to the synthesis of a variety of chemical products.
Used in Agrochemical Production:
2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE is employed as an intermediate in the manufacture of agrochemicals, playing a crucial role in the development of pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Medicinal Chemistry Research:
2-PHENYL-1,3-THIAZOLE-4-CARBOHYDRAZIDE is used as a subject of study in medicinal chemistry for its potential biological and pharmacological activities, which may lead to the discovery of new therapeutic agents and treatments.

InChI:InChI=1/C10H9N3OS/c11-13-9(14)8-6-15-10(12-8)7-4-2-1-3-5-7/h1-6H,11H2,(H,13,14)

Upstream product

• 59937-01-8 2-phenylthiazole-4-carboxylic acid ethyl ester 
• 2227-79-4 benzenecarbothioamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 7171-34-8 2-Phenyl-4-acetoamidothiazole 
• 1257901-94-2 2-(2-phenylthiazol-4-yl)-1,3,4-oxadiazole 
• 1219827-72-1 5-(2-phenylthiazol-4-yl)-1,3,4-oxadiazole-2-amine 
• 1416716-44-3 5-(2-phenylthiazol-4-yl)-1,3,4-oxadiazole-2(3H)-one 
• 338760-49-9 5-(2-phenylthiazol-4-yl)-1,3,4-oxadiazole-2(3H)-thione 
• 1416716-55-6 [5-amino-4-(ethyloxycarbonyl)-1H-pyrazol-1-yl](2-phenylthiazol-4-yl)methanone 
• 1416716-57-8 (5-amino-3-phenyl-1H-pyrazol-1-yl)(2-phenylthiazol-4-yl)methanone 
• 1416716-49-8 4-{2-[5-(2-phenylthiazol-4-yl)-1,3,4-oxadiazol-2-ylthio]ethyl}morpholine 
• 1416716-51-2 {2-[5-(2-phenylthiazol-4-yl)-1,3,4-oxadiazol-2-ylthio]ethyl}dimethylamine 
• 1416716-53-4 5-(2-phenylthiazol-4-yl)-3-(piperidin-1-ylmethyl)-1,3,4-oxadiazole-2(3H)-thione 
• 1338372-60-3 (R)-(4-fluorophenyl)(8-methyl-3-(2-phenylthiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone 

Relevant articles and documents

I2/TBHP-Mediated tandem cyclization and oxidation reaction: Facile access to 2-substituted thiazoles and benzothiazoles

The efficient synthesis of 2-substituted thiazoles and benzothiazoles has been accomplished employing readily available cysteine esters and 2-aminobenzenethiols as N and S sources. The reaction proceeds under an I2/TBHP system and involves a on

Docking, synthesis, and pharmacological investigation of novel substituted thiazole derivatives as non-carboxylic, anti-inflammatory, and analgesic agents

A series of substituted thiazole derivatives (6-16) were synthesized to obtain new compounds with potential anti-inflammatory and analgesic activities. At equimolar oral doses, compounds 3-(piperidin-1-yl-methyl)-1, 3, 4-oxadiazol-2-thione (14), 5-amino-4