71170-89-3 Usage
Uses
Used in Pharmaceutical Research:
N-CBZ-2-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER is used as an intermediate in the synthesis of various pharmaceuticals and biologically active compounds. Its role in the production process is crucial for creating a range of medications that target different health conditions.
Used in Organic Synthesis:
In the field of organic synthesis, N-CBZ-2-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER is utilized as a key component in the creation of complex organic molecules. Its unique structure allows it to participate in various chemical reactions, contributing to the development of new organic compounds.
Used as a Protecting Group in Peptide Synthesis:
N-CBZ-2-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER is used as a protecting group in peptide synthesis to shield the amino group of the piperidine ring. This protection is essential during the synthesis process to prevent unwanted side reactions and ensure the correct formation of peptide bonds.
Check Digit Verification of cas no
The CAS Registry Mumber 71170-89-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,7 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71170-89:
(7*7)+(6*1)+(5*1)+(4*7)+(3*0)+(2*8)+(1*9)=113
113 % 10 = 3
So 71170-89-3 is a valid CAS Registry Number.
71170-89-3Relevant articles and documents
Ring-Strain Effects in Base-Induced Sommelet–Hauser Rearrangement: Application to Successive Stereocontrolled Transformations
Tayama, Eiji,Watanabe, Kazutoshi,Matano, Yoshihiro
supporting information, p. 3631 - 3641 (2016/07/29)
The base-induced Sommelet–Hauser (S–H) rearrangement of azetidine-2-carboxylic acid ester-derived ammonium salts into 2-aryl-substituted derivatives was demonstrated. The ring-strain of four-membered N-heterocycles enables efficient generation of the desired ylide intermediate and enhances the rate of the S–H rearrangement. The asymmetric version of the rearrangement was characterized by excellent levels of successive chirality transmissions. The regio- and stereo-controlled nucleophilic ring opening of the rearrangement products produced quaternary α-aryl amino acid esters with excellent enantiopurities.
Design, Synthesis, and X-ray Crystallographic Analysis of Two Novel Spirolactam Systems as β-Turn Mimics
Genin, Michael J.,Gleason, William B.,Johnson, Rodney L.
, p. 860 - 866 (2007/10/02)
Two novel 5.4-spirolactam systems have been developed as β-turn mimics.The (R)-5.4-spirolactam system of 4 was designed to mimic the type-II β-turn, and the (S)-5.4-spirolactam system of 5 was designed to mimic the type-II' β-turn.The 5.4-spirolactam dipe