799766-13-5

Basic information

• Product Name: Benzofuran, 7-bromo-4-methyl- (9CI)
• Synonyms: Benzofuran, 7-bromo-4-methyl- (9CI);7-Bromo-4-methylbenzofuran;7-broMo-4-Methyl-1-benzofuran
• CAS NO: 799766-13-5
• Molecular Formula: C₉H₇BrO
• Molecular Weight: 211.05528
• Product Categories: METHYL
• Mol File: 799766-13-5.mol

Chemical Properties

• Boiling Point: 261.5 °C at 760 mmHg
• Flash Point: 111.9 °C
• Appearance: /
• Density: 1.52 g/cm³
• Vapor Pressure: 0.0187mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Benzofuran, 7-bromo-4-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 7-bromo-4-methyl- (9CI)(799766-13-5)
• EPA Substance Registry System: Benzofuran, 7-bromo-4-methyl- (9CI)(799766-13-5)

Safety Data

• Hazardous Substances Data: 799766-13-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Benzofuran, 7-bromo-4-methyl(9CI) is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Benzofuran, 7-bromo-4-methyl(9CI) is utilized as a key intermediate in the development of new drugs. Its unique chemical properties make it a promising candidate for the synthesis of bioactive molecules with potential therapeutic applications.
Used in Drug Development:
Due to its unique structural and chemical properties, Benzofuran, 7-bromo-4-methyl(9CI) may have potential applications in the development of new drugs. It can be used as a starting material or a component in the synthesis of pharmaceutical compounds with novel therapeutic effects.
Safety Precautions:
As with any chemical compound, proper handling and safety precautions should be observed when working with Benzofuran, 7-bromo-4-methyl(9CI). This includes wearing appropriate personal protective equipment, working in a well-ventilated area, and following established safety protocols to minimize potential risks.

InChI:InChI=1/C9H7BrO/c1-6-2-3-8(10)9-7(6)4-5-11-9/h2-5H,1H3

Upstream product

• 14847-51-9 2-bromo-5-methylphenol 
• 799766-12-4 1-bromo-2-(2,2-dimethoxy-ethoxy)-4-methylbenzene 

Downstream Products

• 5670-23-5 4-methyl-benzofuran 
• 799766-16-8 7-(4-hydroxyphenyl)-benzofuran-4-carbaldehyde 
• 799766-15-7 7-(4-methoxyphenyl)-benzofuran-4-carbaldehyde 
• 799766-14-6 7-(4-methoxyphenyl)-4-methylbenzofuran 

Relevant articles and documents

OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF

The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.

ERβ ligands. Part 5: Synthesis and structure-activity relationships of a series of 4′-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

A series of 4′-hydroxyphenyl-aryl-carbaldehyde oximes (5b) was prepared and found to have high affinity (4 nM) and modest selectivity (39-fold) for estrogen receptor-β (ERβ). Substitution of one of the core rings of the scaffold based around these novel ligands further expanded our knowledge in the quest toward achieving high affinity and selectivity for ERβ. An X-ray co-crystal of structure 11 revealed that the oxime moiety was mimicking the C-ring of genistein, as previously predicted by SAR and docking studies.

ARYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS

This invention provides estrogen receptor modulators having the structure (I) where R1-R5 are as defined in the specification; or a pharmaceutically acceptable salt thereof.