5670-23-5

Usage

Uses

Used in Flavor and Fragrance Industry:
4-methylbenzofuran is used as a flavor and fragrance ingredient for its distinctive sweet odor, adding unique scents and tastes to various food and cosmetic products.
Used in Pharmaceutical Industry:
4-methylbenzofuran is used as a synthetic intermediate in the production of pharmaceuticals, contributing to the development of new drugs and organic compounds.
Used in Cosmetic Industry:
4-methylbenzofuran is used in the cosmetic industry for its distinctive sweet odor, enhancing the sensory experience of cosmetic products.

InChI:InChI=1/C9H8O/c1-7-3-2-4-9-8(7)5-6-10-9/h2-6H,1H3

Upstream product

• 5670-24-6 4-methylbenzofuran-2-carboxylic acid 
• 108-39-4 3-methyl-phenol 
• 58042-45-8 3-methylphenoxyacetaldehyde diethyl acetal 
• 110-00-9 furan 
• 534-22-5 2-methylfuran 
• 799766-13-5 7-bromo-4-methylbenzofuran 
• 14847-51-9 2-bromo-5-methylphenol 
• 18362-36-2 2-hydroxy-6-methylbenzaldehyde 

Relevant academic research and scientific papers

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.

Preparation method of benzofuran compound

The invention relates to a preparation method of a benzofuran compound. The preparation method comprises the following steps: putting a furan compound, acetic acid and a Lewis acid catalyst in a reaction vessel, reacting for 0.5-24 h at 80-160 DEG C, and separating and purifying to obtain the benzofuran compound. According to the preparation method provided by the invention, the furan compound isused as a reaction raw material, an acetic acid water solution is used as a solvent, Lewis acid is used as a catalyst, and at a mild reaction temperature (80-160 DEG C), the benzofuran compound is directly obtained through one-step reaction. The preparation method provided by the invention can synthesize the benzofuran compound with a corresponding structure and functional groups based on the structure and functional groups of the furan compound as a raw material, the raw material components are simple , and the process is convenient to operate; wherein the selectivity of the obtained benzofuran is as high as 99% in the process of synthesizing benzofuran by using furan, so that the method has industrial application prospects.

OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF

The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.

Zeolite-catalyzed synthesis of 2,3-unsubstituted benzo[b]furans via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals

An efficient and environmentally benign heterogeneous catalytic process for the synthesis of 2,3-unsubstituted benzo[b]furans has been established via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals. By utilizing tin-exchanged H-β zeolite (Sn-β) as catalyst, a wide range of functionalized 2,3-unsubstituted benzo[b]furans could be prepared in good to excellent yields. The Sn-β zeolite catalyst also exhibited excellent shape selectivity on the cyclization of meta-substituted 2-aryloxyacetaldehyde acetals, and 6-substituted isomers were preferably formed up to 97% regio-selectivity. Moreover, Sn-β zeolite could be easily recovered and reused without any noticeable activity loss.