14847-51-9

Basic information

• Product Name: 2-bromo-5-methyl-phenol
• Synonyms: 2-bromo-5-methyl-phenol;Nsc21719;Phenol, 2-bromo-5-methyl-
• CAS NO: 14847-51-9
• Molecular Formula: C₇H₇BrO
• Molecular Weight: 187.04
• Mol File: 14847-51-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 38.8°C
• Boiling Point: 209°C (rough estimate)
• Flash Point: 85.8 °C
• Appearance: /
• Density: 1.3839 (rough estimate)
• Vapor Pressure: 0.0863mmHg at 25°C
• Refractive Index: 1.5772 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• PKA: 8.54±0.10(Predicted)
• CAS DataBase Reference: 2-bromo-5-methyl-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-5-methyl-phenol(14847-51-9)
• EPA Substance Registry System: 2-bromo-5-methyl-phenol(14847-51-9)

Safety Data

• Hazardous Substances Data: 14847-51-9(Hazardous Substances Data)

Usage

General Description

2-bromo-5-methyl-phenol is a chemical compound with the molecular formula C7H7BrO. It is a derivative of phenol and is used in the production of pharmaceuticals, dyes, and other organic compounds. 2-bromo-5-methyl-phenol is a white to pale yellow crystalline solid with a characteristic phenolic odor. 2-bromo-5-methyl-phenol is a potent antimicrobial agent and is commonly used as a disinfectant and preservative in various industrial and commercial applications. It is also used in the synthesis of other organic compounds and as a reagent in chemical reactions. Additionally, it has potential applications in the field of medicine and biotechnology due to its antimicrobial properties.

InChI:InChI=1/C7H7BrO/c1-5-2-3-6(8)7(9)4-5/h2-4,9H,1H3

Upstream product

• 53078-85-6 2-bromo-5-methylaniline 
• 2835-98-5 2-Hydroxy-4-methylanilin 
• 67-66-3 chloroform 
• 7726-95-6 bromine 
• 108-39-4 3-methyl-phenol 
• 22356-80-5 2-hydroxy-4-methylbenzenesulfonic acid 
• 700-38-9 2-nitro-5-methylphenol 
• 591-24-2 3-Methylcyclohexanone 
• 7664-93-9 sulfuric acid 
• 7446-11-9 sulfur trioxide 
• 57234-27-2 1-(methoxymethoxy)-3-methylbenzene 

Downstream Products

• 13321-76-1 2,4-dibromo-5-methylphenol 
• 100477-79-0 2,6-Dibrom-3-methylphenol 
• 5415-39-4 6-bromo-2,4-dichloro-3-methyl-phenol 
• 105901-14-2 1-bromo-4-methyl-2-(2-nitrophenoxy)benzene 
• 106037-54-1 (2-bromo-5-methyl-phenyl)-(4-methyl-2-nitro-phenyl)-ether 
• 73286-62-1 (-)-2-Bromo-5-methylphenyl (Isopinocampheyloxy)methyl Ether 
• 95740-49-1 1-bromo-2-methoxy-4-methylbenzene 
• 52905-06-3 2-bromo-5-methylphenyl benzenesulfonate 
• 112135-31-6 2-bromo-4-chloro-5-methylphenol 
• 137408-21-0 3(4)-vinylbenzyl alcohol 

Relevant articles and documents

Selectivity enhancement of aromatic halogenation reactions at the micellar interface: Effect of highly ionic media

Halogenation (iodination and bromination) of various aromatic compounds has been studied in micellar media in order to observe the effect on regioselectivity and conversion of the reaction. The addition of surfactant causes a change in the chemical shifts of the aromatic proton resonance of phenol which proves the orientation of the aromatic compound on the micellar surface. However, increase in ionic strength of the reaction media affects the selectivity of reaction by disturbing this spatial orientation of the aromatic compound in the micelle. Selectivity towards particular isomers is dependent on the concentration of the surfactant. In bromination of chlorobenzene (deactivated aromatic compound) enhancement in selectivity and conversion towards the para isomer has been observed.

A practical highly selective oxybromination of phenols with dioxygen

A simple, low cost and highly selective method for the synthesis of mono-bromophenols from phenol and electron-rich phenolic compounds has been developed. Bromide ions are used as halogenating agents, dioxygen as a final oxidant, and Cu(OAc)2 as a catalyst.

Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists

Novel biphenyl sulfonamide compounds which are combined angiotensin and endothelin receptor antagonists are claimed along with methods of using such compounds in the treatment of conditions such as hypertension and other diseases, as well as pharmaceutica