80036-89-1

Basic information

• Product Name: Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate
• Synonyms: 2-methoxy-4-amino-5-ethysulfonyl benzoic acid methyl ester;Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate;METHYL 4-AMINO-5-(ETHYLSULPHONYL)-2-METHOXYBENZOATE;2-methoxyl-4-amine-5-ethylsulfonyl methyl benzoate;2-Methoxyl-4-Amino-5-Ethylsulfonyl Methyl Benzoate;2-Methoxy-4-amino-5-ethsulfonyl benzoic acid methyl ester;2-METHOXYL-4-AMINO-5-ETHYLSULFONYLBENZOIC METHYL ESTER;methyl 4-amino-5-(ethylsulfonyl)-2-methoxybenzoat
• CAS NO: 80036-89-1
• Molecular Formula: C11H15NO5S
• Molecular Weight: 273.31
• EINECS: 1308068-626-2
• Mol File: 80036-89-1.mol

Chemical Properties

• Boiling Point: 514.5 °C at 760 mmHg
• Flash Point: 265 °C
• Appearance: /
• Density: 1.289 g/cm³
• Vapor Pressure: 1.07E-10mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -2.97±0.13(Predicted)
• CAS DataBase Reference: Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate(80036-89-1)
• EPA Substance Registry System: Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate(80036-89-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 80036-89-1(Hazardous Substances Data)

Usage

Uses

Methyl 4-amino-5-(ethylsulphonyl)-2-methoxybenzoate is a useful research chemical.

InChI:InChI=1/C11H15NO5S/c1-4-18(14,15)10-5-7(11(13)17-3)9(16-2)6-8(10)12/h5-6H,4,12H2,1-3H3

Upstream product

• 4093-29-2 methyl 4-(acetylamino)-o-anisate 
• 59168-56-8 methyl 4-amino-2-methoxy-5-thiocyanatobenzoate 
• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 
• 65-49-6 4-Aminosalicylic acid 

Relevant articles and documents

Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid

The invention discloses a preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid, and the preparation method comprises the following steps: taking 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid as a raw material; the preparation method comprises five steps of methylation, thiocyanation, ethylation, oxidation and a hydrolysis reaction, and finally, 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid is prepared. The preparation method provided by the invention can efficiently prepare 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid under mild reaction conditions, only uses ethanol and water as solvents, has the advantages of simple operation, high yield, good product quality, less three wastes, low cost and the like, and is convenient for large-scale production.

A halogen halide for preparing 2-methoxy-4-amino-5-b sulfuryl method of methyl benzoate

The invention relates to a method for preparing 2-methoxy-4-amino-5-ethysulfonyl benzoic acid methyl ester by halogen halogenation. According to the invention, 2-methoxy-4-acetyl methyl anthranilate is subjected to halogen halogenation (chlorination, bromination or iodization) and then is condensed with sodium ethanesulfinate to obtain a target product. The method has the advantages that the process route is simple, the product yield is high, the total yield reaches 80 percent, the product quality is high, the purity reaches 99.5 percent, and the appearance is white.