4093-29-2

Basic information

• Product Name: Methyl 4-acetamido-2-methoxybenzoate
• Synonyms: 4-acetamide-2-methoxybenzoicacid-methylester;Methyl4-acetylamino-2-methoxybenzoate;4-ACETYLAMINO-2-METHOXY-BENZOIC ACID METHYL ESTER;METHYL 4-ACETAMIDO-2-METHOXYBENZOATE;methyl 4-(acetylamino)-o-anisate;4-ACETAMIDO-2-METHOXYBENZOIC ACID METHYL ESTER;METHYL4-ACETAMINO-2-METHOXYBENZOATE;4-ACETYLAMINO-2-METHOXYBENZOATE
• CAS NO: 4093-29-2
• Molecular Formula: C₁₁H₁₃NO₄
• Molecular Weight: 223.23
• EINECS: 223-839-6
• Mol File: 4093-29-2.mol
• Article Data: 17

Chemical Properties

• Melting Point: 128.0 to 132.0 °C
• Boiling Point: 417.5 °C at 760 mmHg
• Flash Point: 206.3 °C
• Appearance: /
• Density: 1.21 g/cm³
• Vapor Pressure: 3.52E-07mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
• PKA: 14.09±0.70(Predicted)
• CAS DataBase Reference: Methyl 4-acetamido-2-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-acetamido-2-methoxybenzoate(4093-29-2)
• EPA Substance Registry System: Methyl 4-acetamido-2-methoxybenzoate(4093-29-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4093-29-2(Hazardous Substances Data)

Usage

Uses

Methyl 4-acetamido-2-methoxybenzoate (Metoclopramide EP Impurity D) is an impurity of bromopride (B686645), which is an antiemetic.

InChI:InChI=1/C11H13NO4/c1-7(13)12-8-4-5-9(11(14)16-3)10(6-8)15-2/h4-6H,1-3H3,(H,12,13)

Upstream product

• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 
• 75-36-5 acetyl chloride 
• 39106-79-1 methyl 2-methoxy-4-nitrobenzoate 
• 4093-28-1 methyl 4-acetamido-2-hydroxybenzoate 
• 77-78-1 dimethyl sulfate 
• 50-86-2 4-acetamidosalicylic acid 
• 584-08-7 potassium carbonate 
• 4136-97-4 methyl 4-aminosalicylate 
• 65-49-6 4-Aminosalicylic acid 
• 74-88-4 methyl iodide 
• 108-24-7 acetic anhydride 
• 67-56-1 methanol 
• 55304-05-7 4-acetylamino-2-methoxy-benzoic acid 

Downstream Products

• 1304076-79-6 2-hydroxybenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-80-9 4-hydroxybenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 908089-55-4 4-hydroxy-3-methoxy-benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-86-5 C₁₉H₁₉N₃O₄S 
• 908085-10-9 C₁₉H₁₈ClN₃O₄S 
• 1304076-87-6 C₁₉H₁₉N₃O₅S 
• 1304076-88-7 C₁₉H₁₉N₃O₅S 
• 908085-25-6 C₂₀H₂₁N₃O₆S 
• 1304076-92-3 C₂₀H₂₁N₃O₅S 
• 1304076-70-7 4-acetamido-2-methoxybenzoyl hydrazine 
• 1304076-74-1 benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-77-4 4-chlorobenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1388193-49-4 Br^(1-)*C₃₁H₃₄ClN₂O₇⁽¹⁺⁾ 
• 1388193-50-7 Br^(1-)*C₃₁H₃₄ClN₂O₇⁽¹⁺⁾ 

Relevant articles and documents

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I' PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

As neuroprotective agents of pharmaceutical compounds

The invention discloses a medicinal compound as a neuroprotective agent. The medicinal compound is a neuronal nitric oxide synthase-postsynaptic density protein 95 (nNOS-PSD95) decoupling agent. The medicinal compound is a benzene ring derivative shown in the general formula (I) or its pharmaceutically acceptable salt. The invention further discloses a preparation method of the medicinal compound and a use of the medicinal compound in prevention and treatment on neuronal damage influence-caused diseases.

Substituted benzene and heterocyclic compound and its preparation method and application

The invention provides substituted benzoheterocyclic compounds and a preparation method thereof. The compounds have structures shown by formulas I and II. The invention also provides the effects of the compounds shown by formulas I and II in resisting virus, tumor and the like. The invention further provides a medicine composition taking the compounds shown by the formulas I and II as active ingredients, and the anti-virus or anti-tumor effect of the medicine composition. The invention lays a foundation for the future in-depth study and development of the anti-virus or anti-tumor medicine of the compounds.