81250-34-2Relevant articles and documents
BIOLOGICALLY-ACTIVE 1,3-DIPROPYL-8-PHENYLXANTHINE DERIVATIVES
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, (2008/06/13)
Certain functionalized congeners of 1,3-dialkylxanthine exhibit high potency and selectivity as antagonists for A 1-and A. sub.2-adenosine receptors and are suitable for attachment to probes, drug carriers, or solid supports. These derivatives are characterized by the presence of a phenyl at the 8 position para-substituted with a functionalized chain to provide high water solubility and high receptor affinity to such an extent that these compounds are suitable for use as antiallergenic, antiasthmatic, or cardiotonic drugs, central nervous system stimulants, and diuretics.
Substituted 8-phenylxanthines
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, (2008/06/13)
Substituted 8-phenylxanthines and their use as bronchodilators is described. Methods for their preparation and use as well as pharmaceutical compositions containing them are also described.