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MPEG4-CH2CH2COOH, also known as m-PEG5-acid, is a PEG (polyethylene glycol) linker with a terminal carboxylic acid group. This terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC or HATU to form a stable amide bond. The hydrophilic PEG spacer enhances solubility in aqueous media, making it a versatile molecule for various applications.

81836-43-3

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81836-43-3 Usage

Uses

Used in Bioconjugation:
MPEG4-CH2CH2COOH is used as a PEG linker for bioconjugation purposes. The terminal carboxylic acid allows for the formation of stable amide bonds with primary amine groups on biomolecules, such as proteins or peptides, facilitating the attachment of these molecules to the PEG chain.
Used in Drug Delivery Systems:
In the pharmaceutical industry, MPEG4-CH2CH2COOH is used as a component in drug delivery systems. The PEG spacer improves the solubility and stability of drug molecules, while the terminal carboxylic acid enables the attachment of drug molecules to the PEG chain, potentially enhancing their therapeutic efficacy and reducing side effects.
Used in Diagnostic Imaging:
In the field of diagnostic imaging, MPEG4-CH2CH2COOH is used as a PEG linker for the attachment of imaging agents to biomolecules. The hydrophilic PEG spacer can improve the solubility and circulation time of imaging agents, while the terminal carboxylic acid allows for the formation of stable amide bonds with primary amine groups on the imaging agents.
Used in Hydrogels:
In the biomedical engineering field, MPEG4-CH2CH2COOH is used as a component in the synthesis of hydrogels. The PEG spacer contributes to the hydrophilic nature and biocompatibility of the hydrogel, while the terminal carboxylic acid can be used to crosslink the PEG chains, forming a stable hydrogel network for various applications, such as tissue engineering or drug delivery.

Check Digit Verification of cas no

The CAS Registry Mumber 81836-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,8,3 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81836-43:
(7*8)+(6*1)+(5*8)+(4*3)+(3*6)+(2*4)+(1*3)=143
143 % 10 = 3
So 81836-43-3 is a valid CAS Registry Number.

81836-43-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5,8,11,14-pentaoxaheptadecan-17-oic acid

1.2 Other means of identification

Product number -
Other names mPEG4-CH2CH2COOH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81836-43-3 SDS

81836-43-3Relevant articles and documents

Deep cavitand vesicles - Multicompartmental hosts

Kubitschke, Jens,Javor, Sacha,Rebek, Julius

, p. 9251 - 9253 (2012/09/21)

The synthesis and characterization of vesicles assembled from deep cavitands in water is reported. These vesicles act as hosts for three different types of guests: the cavitands bind small guest molecules, the bilayer attracts larger hydrophobic guests an

Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof

-

Page/Page column 32, (2008/06/13)

Fatty acid compositions for administration of of pharmaceutical agents, such as proteins and peptides, protein and peptide conjugates, and/or cation-polypeptide conjugate complexes. In particular, the invention provides a solid pharmaceutical composition

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