82551-63-1

Basic information

• Product Name: 4-Nitrobenzyl 2-diazoacetoacetate
• Synonyms: p-Nitrobenzyl 2-diazoacetoacetate;p-Nitrobenzyl-diazoacetoacetate;4-Nitrobenzyl 2-diazoacetoacetate;2-diazo-5-(4-nitrophenyl)-3-oxopentanoate;Butanoic acid,2-diazo-3-oxo-, (4-nitrophenyl)Methyl ester;4-nitrobenzyl 2-diazo-3-oxobutanoate;p-Nitrobenzyl -diazoacetoacetate: p-Nitrobenzyl 2-diazoacetoacetate
• CAS NO: 82551-63-1
• Molecular Formula: C₁₁H₉N₃O₅
• Molecular Weight: 263.21
• EINECS: 1806241-263-5
• Product Categories: pharmaceutical intermediates
• Mol File: 82551-63-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Nitrobenzyl 2-diazoacetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitrobenzyl 2-diazoacetoacetate(82551-63-1)
• EPA Substance Registry System: 4-Nitrobenzyl 2-diazoacetoacetate(82551-63-1)

Safety Data

• Hazardous Substances Data: 82551-63-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-Nitrobenzyl 2-diazoacetoacetate is used as a reagent for generating carbenes, which are highly reactive intermediates in organic chemistry. These carbenes are employed in a variety of synthetic transformations, such as cyclopropanation, insertion reactions, and C-H functionalization.
Used in the Synthesis of Complex Molecular Architectures:
4-Nitrobenzyl 2-diazoacetoacetate is used as a valuable tool for accessing complex molecular architectures due to its ability to insert into C-H bonds of various organic compounds. This property makes it a useful component in the development of novel chemical entities and pharmaceuticals.
Used in Research and Development:
In the research and development industry, 4-Nitrobenzyl 2-diazoacetoacetate is used as a key compound for exploring new chemical reactions and mechanisms, contributing to the advancement of organic chemistry and the discovery of new synthetic pathways.

InChI:InChI=1/C11H9N3O5/c1-7(15)10(13-12)11(16)19-6-8-2-4-9(5-3-8)14(17)18/h2-5H,6H2,1H3

Upstream product

• 61312-84-3 4-nitrobenzyl 3-oxobutanoate 
• 134973-72-1 2-diazoacetoacetic acid 
• 619-73-8 4-nitrobenzyl chloride 
• 79791-38-1 4-dodecylbenzenesulphonyl azide 
• 105-45-3 acetoacetic acid methyl ester 
• 941-55-9 4-toluenesulfonyl azide 
• 2009-97-4 ethyl 2-diazo-3-oxobutanoate 

Downstream Products

• 86269-29-6 (Z)-(2S,8R,9S)-3,3,6-Trimethyl-10-oxo-9-(2-phenoxy-acetylamino)-7-oxa-4-thia-1-aza-bicyclo[6.2.0]dec-5-ene-2,5-dicarboxylic acid 2-benzyl ester 5-(4-nitro-benzyl) ester 
• 86288-03-1 (Z)-2-[(2R,3R)-1-((R)-1-Benzyloxycarbonyl-2-methyl-allyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-oxo-azetidin-2-ylsulfanyl]-3-hydroxy-but-2-enoic acid 4-nitro-benzyl ester 
• 100163-31-3 secopenicillin 
• 93788-47-7 p-nitrobenzyl 2-diazo-3-(trimethylsilyl)oxy-3-butenoate 
• 86255-96-1 (Z)-(2S,8R,9R)-9-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3,3,6-trimethyl-10-oxo-7-oxa-4-thia-1-aza-bicyclo[6.2.0]dec-5-ene-2,5-dicarboxylic acid 2-benzyl ester 5-(4-nitro-benzyl) ester 
• 86255-97-2 (Z)-2-[(2R,3S)-1-((R)-1-Benzyloxycarbonyl-2-methyl-allyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-oxo-azetidin-2-ylsulfanyl]-3-hydroxy-but-2-enoic acid 4-nitro-benzyl ester 
• 86255-97-2 (Z)-2-[(2R,3S)-1-((R)-1-Benzyloxycarbonyl-2-methyl-allyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-oxo-azetidin-2-ylsulfanyl]-3-hydroxy-but-2-enoic acid 4-nitro-benzyl ester 
• 86269-28-5 (Z)-(2S,8R,9S)-3,3,6-Trimethyl-10-oxo-9-phenylacetylamino-7-oxa-4-thia-1-aza-bicyclo[6.2.0]dec-5-ene-2,5-dicarboxylic acid 2-methyl ester 5-(4-nitro-benzyl) ester 
• 74288-39-4 (3S,4R)-3-[(R)-1-hydroxyethyl)-4-[3-(4-nitrobenzyl)oxycarbonyl-2-oxo-3-diazopropyl]azetidin-2-one 
• 98269-57-9 3-(1-methylethylidene)-4-<3-(((p-nitrobenzyl)oxy)carbonyl)-3-diazo-2-oxopropyl>-2-azetidinone 
• 98391-92-5 3-<(E)-1-methyl-2-((((p-nitrobenzyl)oxy)carbonyl)oxy)ethylidene>-4-<3-(((p-nitrobenzyl)oxy)carbonyl)-3-diazo-2-oxopropyl>-2-azetidinone 
• 98269-71-7 1-(tert-butyldimethylsilyl)-3-<(E)-1-methyl-2-((((p-nitrobenzyl)oxy)carbonyl)oxy)ethylidene>-4-<3-(((p-nitrobenzyl)oxy)carbonyl)-3-diazo-2-oxopropyl>-2-azetidinone 
• 98269-63-7 3-<(E)-2-bromo-1-methylethylidene>-4-<3-(((p-nitrobenzyl)oxy)carbonyl)-3-diazo-2-oxopropyl>-2-azetidinone 
• 93861-39-3 (3S,4R)-3-[(1R)-(tert-butyldimethyl-silyloxy)ethyl]-4-[3-(4-nitrobenzyloxy)carbonyl-2-oxo-3-diazopropyl]azetidin-2-one 

Relevant articles and documents

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