82957-07-1Relevant articles and documents
BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS
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Page/Page column 161; 162, (2014/02/15)
Disclosed herein are novel pharmaceutical agents which are useful as integrin receptor antagonists that mediate the pathologic processes of angiogenesis and fibrosis and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by these integrins by inhibiting or antagonizing these integrins. The novel pharmaceutical agents include those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods and intermediates useful for making the pharmaceutical agents and methods of using the pharmaceutical agents are also provided.
META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS
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, (2008/06/13)
The present invention relates to a class of compounds represented by the Formula Ior a pharmaceutically acceptable salt thereof, whereinA ispharmaceutical compositions thereof and methods of using such compounds and compositions as alphavbeta3 antagonists.
Synthesis of esters of guanidinobenzoic acids and guanidinomethylbenzoic acids with antiproteolytic activity
Wagner,Vieweg,Kuehmstedt
, p. 293 - 296 (2007/10/06)
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