860789-75-9

Basic information

• Product Name: 6,8-dibromo-2-phenylquinoline
• Synonyms: 6,8-dibromo-2-phenylquinoline
• CAS NO: 860789-75-9
• Molecular Weight: 363.051
• Mol File: 860789-75-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 6,8-dibromo-2-phenylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-dibromo-2-phenylquinoline(860789-75-9)
• EPA Substance Registry System: 6,8-dibromo-2-phenylquinoline(860789-75-9)

Safety Data

• Hazardous Substances Data: 860789-75-9(Hazardous Substances Data)

Upstream product

• 19433-17-1 acetophenone O-acetyloxime 
• 50739-76-9 (2-amino-3,5-dibromophenyl)methanol 
• 98-86-2 acetophenone 
• 861787-48-6 3,5-dibromo-2-nitro-benzaldehyde 
• 98-85-1 1-Phenylethanol 
• 24005-23-0 2-phenyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Mild and efficient copper-catalyzed oxidative cyclization of oximes with 2-aminobenzyl alcohols at room temperature: synthesis of polysubstituted quinolines

A simple and efficient ligand-free Cu-catalyzed protocol for the synthesis of polysubstituted quinolinesviaoxidative cyclization of oxime acetates with 2-aminobenzyl alcohols at room temperature has been developed. The presented approach provides a new synthetic pathway leading to polysubstituted quinolines with good functional group tolerance under mild conditions. Moreover, this transformation can be applied for the preparation of quinolines on a gram scale. Oxime acetates serve as the internal oxidants in the reactions, thus making this method very attractive.

Visible-Light-Mediated Oxidative Cyclization of 2-Aminobenzyl Alcohols and Secondary Alcohols Enabled by an Organic Photocatalyst

This paper describes a visible-light-mediated oxidative cyclization of 2-aminobenzyl alcohols and secondary alcohols to produce quinolines at room temperature. This photocatalytic method employed anthraquinone as an organic small-molecule catalyst and DMSO as an oxidant. According to this present procedure, a series of quinolines were prepared in satisfactory yields.

Efficient access to quinolines and quinazolines by ruthenium complexes catalyzed acceptorless dehydrogenative coupling of 2-aminoarylmethanols with ketones and nitriles

Treatment of N,N,O-tridentate pyrazolyl-pyridinyl-alcohol ligands, 2-(CR1R2OH)-6-[3,5-(R3)2C3HN2]C5H3N (R1 = R2 = Me, R3 = H (L1H); R1 = Me, R2 = Ph, R3 = H (L2H); R1 = R2 = Ph, R3 = H (L3H); R1 = R2 = R3 = Me (L4H)) with RuCl3?xH2O in refluxing EtOH afforded the corresponding Ru(III) complexes L2RuCl (1a-1d), which were well characterized by IR, HR-MS and X-ray single crystal structural determination. These Ru complexes showed similarly high catalytic performance for both dehydrogenative couplings of 2-aminoarylmethanols with ketones and nitriles, giving the quinolines and quinazolines in good to excellent yields. This protocol provides an atom-economical and sustainable route to access various structurally important quinoline and quinazoline derivatives by using phosphine-free ligand based Ru catalysts.