861905-94-4

Usage

Uses

Used in Organic Synthesis:
3-Fluoro-5-iodo-4-methylbenzoic acid is used as a versatile building block in the field of organic synthesis. Its unique structure allows for the creation of a wide range of organic compounds, making it an essential component in chemical research and development.
Used in Pharmaceutical Industry:
3-Fluoro-5-iodo-4-methylbenzoic acid is used as a key intermediate in the production of various pharmaceutical compounds. Its potential application in this industry highlights its importance in the development of new drugs and therapeutic agents.
Safety Considerations:
Due to potential hazards associated with 3-Fluoro-5-iodo-4-methylbenzoic acid, its handling and storage must be done with caution. Proper safety measures should be implemented to minimize risks and ensure the safe use of this chemical compound in various applications.

Upstream product

• 350-28-7 3-fluoro-4-methyl-benzoic acid 
• 65-85-0 benzoic acid 

Downstream Products

• 585544-31-6 N-cyclopropyl-3-fluoro-5-iodo-4-methylbenzamide 
• 861905-21-7 methyl 3-fluoro-5-iodo-4-methylbenzoate 
• 1190862-88-4 3-fluoro-5-iodo-4-methylbenzamide 
• 861905-85-3 1,1-dimethylethyl 3-fluoro-5-iodo-4-methylbenzoate 
• 1232287-22-7 benzyl[2-[2-[1-[[6-bromo-4-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-3-oxo-3,4-dihydro-2-pyrazinyl]amino]cyclopropyl]phenoxy]ethyl]methylcarbamate 
• 1232287-20-5 methyl 3-[3-[1-[2-[2-[(benzyloxycarbonyl)methylamino]ethoxy]phenyl]cyclopropylamino]-5-bromo-2-oxo-1(2H)-pyrazinyl]-5-fluoro-4-methylbenzoate 
• 1095006-01-1 3-(3,5-dibromo-2-oxo-2H-pyrazin-1-yl)-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1232287-16-9 methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt 
• 1232287-18-1 methyl 3-[(diphenylmethylene)amino]-5-fluoro-4-methylbenzoate 
• 1095006-00-0 3-[(cyanomethyl)amino]-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1095004-78-6 N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxopyrazin-1-yl]benzamide 
• 917223-75-7 N-(2,2-dimethylpropyl)-6-{3-fluoro-5-[(3-isoxazolylamino)carbonyl]-2-methylphenyl}-3-pyridinecarboxamide 
• 917223-81-5 3-(5-{[(2,2-dimethylpropyl)amino]carbonyl}-2-pyridinyl)-5-fluoro-4-methylbenzoic acid 
• 917223-88-2 methyl 3-(5-{[(2,2-dimethylpropyl)amino]carbonyl}-2-pyridinyl)-5-fluoro-4-methylbenzoate 

Relevant academic research and scientific papers

NOVEL COMPOUNDS HAVING EFFECTS OF TREATING INFLAMMATORY DISEASE AS P38 MAP KINASE INHIBITOR

The present invention relates to novel compounds exhibiting anti-inflammatory activity. The compound of the present invention plays a critical role in the production of inflammatory prodrug (pro-inflammatory cytokines) and has an excellent inhibitory effe

Expedited Kilolab Development of AZD7624 Using Kulinkovich-de Meijere Cyclopropanation

AZD7624 is a small molecule compound developed for the treatment of chronic obstructive pulmonary disease. This study describes the lab development and kilolab manufacture of the drug substance. A small number of route options were evaluated using lab pro

Crystalline form (by machine translation)

The application relates to a crystalline form of the compound of formula (I).

New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I), to pharmaceutical compositions comprising them, and to their use in therapy.

NEW 7-PHENYL-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3(2H)-ONE DERIVATIVES

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I), to processes for their preparation, to pharmaceutical compositions comprising them, and to their use in therapy.

p38α mitogen-activated protein kinase inhibitors: Optimization of a series of biphenylamides to give a molecule suitable for clinical progression

p38α MAP kinase is a key anti-inflammatory target for rheumatoid arthritis, influencing biosynthesis of pro-inflammatory cytokines TNFα and IL-1β at a translational and transcriptional level. In this paper, we describe how we have optimized a series of no

New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I) to processes for their preparation; to pharmaceutical compositions comprising them; and to their use in therapy.

NICOTINAMIDE DERIVATIVE USED AS A P38 KINASE INHIBITOR

This invention relates to the nictonamide derivative (I): 6- (3-Fluoro-2-methyl-5-{ [ (1-methyl-1H-pyrazol-5-yl) amino] carbonyl} phenyl) -N- (2-m ethylpropyl) -3-pyridinecarboxamide and its use as a pharmaceutical, particularly as a p38 kinase inhibitor,

NEW 3-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-7-YL)BENZAMIDE DERIVATIVES

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I) to processes for their preparation; to pharmaceutical compositions comprising them; and to their use in therapy.