1095006-01-1Relevant articles and documents
Expedited Kilolab Development of AZD7624 Using Kulinkovich-de Meijere Cyclopropanation
Ashok, Mithun,Ashwini, D. j.,Leuser, Helena,Malapati, Ajaya K.,Parker, Jeremy S.,Rowley, Naomi A.,Steven, Alan,Timms, Lee,Tyler, Simon N. G.,Whitmarsh, Samuel
, p. 2351 - 2366 (2021/10/21)
AZD7624 is a small molecule compound developed for the treatment of chronic obstructive pulmonary disease. This study describes the lab development and kilolab manufacture of the drug substance. A small number of route options were evaluated using lab pro
PYRAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF LUNG DISEASES
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, (2009/03/07)
The present invention relates to py razinone derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.