863870-86-4 Usage
General Description
2-Chloro-3-fluorophenol is a chemical compound that belongs to the class of phenol compounds, which are aromatic organic compounds containing a hydroxyl group directly bonded to an aromatic hydrocarbon group. This specific chemical is a phenol derivative with chlorine and fluorine substituents, and it has the molecular formula C6H4ClFO. It is used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. 2-Chloro-3-fluorophenol is also employed as an intermediate in the manufacturing of other organic compounds, and it may have potential applications in the field of medicinal chemistry and drug development. Additionally, it is important to handle this chemical with care, as it is considered hazardous and may pose health risks if not handled properly.
Check Digit Verification of cas no
The CAS Registry Mumber 863870-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,8,7 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 863870-86:
(8*8)+(7*6)+(6*3)+(5*8)+(4*7)+(3*0)+(2*8)+(1*6)=214
214 % 10 = 4
So 863870-86-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClFO/c7-6-4(8)2-1-3-5(6)9/h1-3,9H
863870-86-4Relevant articles and documents
Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles
Guilarte, Veronica,Castroviejo, M. Pilar,Garcia-Garcia, Patricia,Fernandez-Rodriguez, Manuel A.,Sanz, Roberto
, p. 3416 - 3437 (2011/06/28)
2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.
