865869-28-9

Basic information

• Product Name: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID
• Synonyms: 4,4-(DIMETHYLCYCLOHEXEN-1-YL)BENZENEBORONIC ACID;4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID;4,4-DIMETHYL-1-CYCLOHEXEN-1-YLBORONIC ACID;4,4-Dimethylcyclohexen-1-ylboronic acid 97%;4,4-DiMethylcyclohexene-1-boronic acid, 96%;(4,4-DiMethylcyclohex-1-en-1-yl)boronic acid;(4,4-Dimethylcyclohex-1-en-1-yl)boronic acid 98%;1-Borono-4,4-dimethylcyclohex-1-ene
• CAS NO: 865869-28-9
• Molecular Formula: C₈H₁₅BO₂
• Molecular Weight: 154.01
• Product Categories: blocks;BoronicAcids
• Mol File: 865869-28-9.mol

Chemical Properties

• Melting Point: 152-154
• Boiling Point: 264.1 °C at 760 mmHg
• Flash Point: 113.5 °C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 0.00138mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: Store below -20C
• PKA: 9.43±0.40(Predicted)
• CAS DataBase Reference: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(865869-28-9)
• EPA Substance Registry System: 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID(865869-28-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 865869-28-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID is used as a reagent for creating carbon-carbon bonds through the Suzuki coupling reaction, a widely employed method in organic synthesis for forming such bonds efficiently and under mild conditions.
Used in Pharmaceutical and Agrochemical Industries:
4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID serves as a building block in the synthesis of various pharmaceuticals and agrochemicals, playing a crucial role in the development of new drugs and pesticides with specific therapeutic or pesticidal properties.
Used in the Creation of Complex Molecules:
In the field of organic chemistry, 4,4-DIMETHYLCYCLOHEXEN-1-YLBORONIC ACID is a valuable tool for creating complex molecules with specific structural and functional properties, enabling the design and synthesis of novel compounds with potential applications in various industries.

InChI:InChI=1/C8H15BO2/c1-8(2)5-3-7(4-6-8)9(10)11/h3,10-11H,4-6H2,1-2H3

Upstream product

• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 64692-81-5 N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide 
• 859217-67-7 2-(4,4-dimethylcyclohex-1-ene-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 954135-66-1 1-[4-amino-3-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-cyclohexanecarbonitrile 
• 915006-53-0 6-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-ylamine 
• 885693-50-5 5-amino-6-(4,4-dimethyl-cyclohex-1-enyl)-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid tert-butyl ester 
• 1403382-29-5 ethyl 2-(tert-butoxy)-2-[2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(trifluoromethyl)phenyl]acetate 
• 1622453-05-7 C₁₅H₁₅F₃N₂ 
• 915006-25-6 2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-ylamine 
• 915006-26-7 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-yl]-amide 
• 907205-86-1 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide 
• 1190962-53-8 4-(2-amino-4-(4,4-dimethylcyclohex-1-en-1-yl)pyrimidin-5-yl)pyridin-3-ol 
• 1190962-51-6 5-(3-chloro-pyridin-4-yl)-4-(4,4-dimethylcyclohex-1-en-1-yl)-pyrimidin-2-amine 
• 1190962-52-7 4-(4,4-dimethylcyclohex-1-en-1-yl)-5-(3-methoxy-pyridin-4-yl)-pyrimidin-2-amine 
• 1190962-54-9 4-(2-amino-4-(4,4-dimethylcyclohex-1-en-1-yl)pyrimidin-5-yl)pyridin-3-yl trifluoromethanesulfonate 
• 954425-01-5 4-[2-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-2-(4,4-dimethyl-cyclohex-1-enyl)-phenylamine 
• 907205-85-0 4-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenylamine 

Relevant articles and documents

Copper-catalyzed tri- or tetrafunctionalization of alkenylboronic acids to prepare tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles

We describe a cascade strategy for tri- or tetrafunctionalization of alkenylboronic acids to prepare diverse tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles in good yields withN-hydroxybenzotriazin-4-one (HOOBT) and arylhydrazines as oxygen and nitrogen sources, respectively. Mechanistic studies reveal that the domino reaction undergoes the copper-catalyzed Chan-Lam reaction, [2,3]-rearrangement, nucleophilic substitution, oxidation and sequential [3,3]-rearrangement over five steps in a one-pot reaction. The reaction shows a broad substrate scope and tolerates a wide range of functional groups. More importantly, the reaction is easily performed at gram scales and the product is purified by simple extraction, washing, and recrystallization without flash column chromatography. The present protocol features easily available starting materials, high site-marked functionalization, five-step cascade in one pot, multiple C-C/C-O/C-N bond formation, and diversity of indole motifs.

Interrupted fischer-indole intermediates via oxyarylation of alkenyl boronic acids

The oxyarylation of alkenyl boronic acids with N-arylbenzhydroxamic acids has been achieved under both copper-mediated and copper-catalyzed conditions to provide access to interrupted Fischer-indole intermediates. This transformation is believed to proceed through a copper-promoted C-O bond forming event followed by a [3,3] rearrangement. The scope of the method is described and mechanistic experiments are discussed.

4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS

Novel antiviral compounds of Formula (I) : wherein: A represents hydroxy; R1 represents aryl, heteroaryl bonded through a ring carbon atom, or heterocyclyl bonded through a ring carbon atom, C1-6alkyl or -C5-9cycloalkyl, each of which may be optionally su