86770-80-1

Basic information

• Product Name: 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE
• Synonyms: 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE;3,3-difluorocyclobutane-1-carbonitrile;3,3-Difluorocyclobutanecarbonitrile - D6209
• CAS NO: 86770-80-1
• Molecular Formula: C₅H₅F₂N
• Molecular Weight: 117.1
• Mol File: 86770-80-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 160.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE(86770-80-1)
• EPA Substance Registry System: 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE(86770-80-1)

Safety Data

• Hazardous Substances Data: 86770-80-1(Hazardous Substances Data)

Usage

General Description

3,3-Difluoro-cyclobutanecarbonitrile is a chemical compound with the molecular formula C5H6F2N. It is a colorless liquid at room temperature and is used in the pharmaceutical and agrochemical industries as an intermediate for the synthesis of various compounds. 3,3-DIFLUORO-CYCLOBUTANECARBONITRILE is also known for its unique structural properties, including a stable cyclobutane ring with two fluorine atoms and a cyano group. It is important to handle this chemical with care due to its potential toxicity and flammability. Additionally, 3,3-Difluoro-cyclobutanecarbonitrile may have applications in organic synthesis and material science due to its versatile reactivity and potential for creating new functionalized molecules.

Upstream product

• 15760-35-7 3-methylenecyclobutanecarbonitrile 
• 20249-16-5 3-oxo-cyclobutanecarbonitrile 

Downstream Products

• 1159813-93-0 1-(3,3-difluorocyclobutyl)-methylamine hydrochloride 
• 1198160-27-8 2-((3,3-difluorocyclobutyl)methyl)-3-oxo-N-(4-(trifluoromethoxy)benzyl)isoindoline-1-carboxamide 
• 1246765-49-0 3,3-difluorocyclobutane-1-carbaldehyde 
• 107496-54-8 3,3-difluorocyclobutanecarboxylic acid 
• 1159882-59-3 1-(3,3-difluorocyclobutyl)methanamine 
• 86770-82-3 3,3-difluorocyclobutane-1-carboxamide 

Relevant articles and documents

AN UNEXPECTED β-ELIMINATION FROM 3,3-DIFLUOROCYCLOBUTANECARBONITRILE

3,3-Difluorocyclobutanecarbonitrile (2) reacts with bases to give β rather than γ-elimination, the latter being the prevailing reaction mode in similar systems.

IMIDAZO[1,2-A]PYRIDINES AS SOLUBLE GUANYLATE CYCLASE STIMULATORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.

9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS

The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as well as a method for preparing these compounds and a pharmaceutical composition comprising the same. The present invention relates also to a use of these compounds in the preparation of a medicament for the treatment and/or prophylaxis of tetracycline drug-sensitive disease. wherein, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7, R8, R9a, R9b, R10, R11, R12, R13a and R13b are each independently as defined in the description.