1159813-93-0

Basic information

• Product Name: (3,3-Difluoro-cyclobutyl)MethanaMine HCl
• Synonyms: (3,3-Difluoro-cyclobutyl)MethanaMine HCl;CyclobutaneMethanaMine, 3,3-difluoro- (hydrochloride)(1:1);(3,3-Difluorocyclobutyl)methylaminehydrochloride
• CAS NO: 1159813-93-0
• Molecular Formula: C₅H₉F₂N*ClH
• Molecular Weight: 157.5894064
• Mol File: 1159813-93-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,3-Difluoro-cyclobutyl)MethanaMine HCl(CAS DataBase Reference)
• NIST Chemistry Reference: (3,3-Difluoro-cyclobutyl)MethanaMine HCl(1159813-93-0)
• EPA Substance Registry System: (3,3-Difluoro-cyclobutyl)MethanaMine HCl(1159813-93-0)

Safety Data

• Hazardous Substances Data: 1159813-93-0(Hazardous Substances Data)

Usage

General Description

"(3,3-Difluoro-cyclobutyl)methanamine HCl" is a chemical compound with significant potential in scientific and industrial applications. This chemical consists of a cyclobutyl ring that has been substituted with two fluorine atoms and a methanamine group. As a hydrochloride (HCl), it falls into the category of organic salts which have unique properties and can be used in diverse ways. The precise properties of this compound, such as its boiling point, melting point, and specific optical rotation, would be determined by its exact structural configuration. Despite its complex structure, (3,3-Difluoro-cyclobutyl)methanamine HCl can be synthesized through a variety of methods. It is crucial to handle this compound with protective equipment due to its possible hazardous effects.

Upstream product

• 86770-80-1 3,3-difluorocyclobutane-1-carbonitrile 
• 7647-01-0 hydrogenchloride 
• 67-56-1 methanol 
• 15760-35-7 3-methylenecyclobutanecarbonitrile 
• 20249-16-5 3-oxo-cyclobutanecarbonitrile 

Relevant articles and documents

Multigram Synthesis of C 4/C5 3,3-Difluorocyclobutyl-Substituted Building Blocks

An approach for the multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks (including carboxylic acid, amines, alcohols, azide, trifluoroborate ketone) is described. It is shown that, in most cases, ethyl 3,3-difluorocyclobutanecarboxylate is a convenient common synthetic intermediate to obtain the target derivatives. For preparation of 3,3-difluorocyclobutanol or -cyclobutanone, an alternative pathway via reaction of dichloroketene and tert -butyl or benzyl vinyl ether should be applied.

9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS

The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as well as a method for preparing these compounds and a pharmaceutical composition comprising the same. The present invention relates also to a use of these compounds in the preparation of a medicament for the treatment and/or prophylaxis of tetracycline drug-sensitive disease. wherein, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7, R8, R9a, R9b, R10, R11, R12, R13a and R13b are each independently as defined in the description.