90301-60-3

Basic information

• Product Name: 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
• Synonyms: 2'-Deoxy-5-(2-hydroxyethyl)uridine;5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE;5-(2-Hyroxyethyl)-2'-deoxyuridine;5-(2-Hyroxyethyl)-2'-deoxyuridine
• CAS NO: 90301-60-3
• Molecular Formula: C₁₁H₁₆N₂O₆
• Molecular Weight: 272.25
• Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Nucleotides
• Mol File: 90301-60-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.496g/cm³
• CAS DataBase Reference: 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE(90301-60-3)
• EPA Substance Registry System: 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE(90301-60-3)

Safety Data

• Hazardous Substances Data: 90301-60-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 90301-60-3 differently. You can refer to the following data:
1. A novel type of potent antiviral nucleoside analog.
2. 5-(2-Hydroxyethyl)-2''-deoxyuridine is a novel type of potent antiviral nucleoside analog.

Upstream product

• 951-78-0 2'-deoxyuridine 
• 90301-69-2 5-(2-chloroethyl)-1-(2-deoxy-3,5-di-O-p-toluoyl-β-D-erythro-pentofuranosyl)-1H,3H-pyrimidine-2,4-dione 
• 51432-34-9 1-(O³,O⁵-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-4-trimethylsilanyloxy-1H-pyrimidin-2-one 
• 624-76-0 Iodoethanol 

Downstream Products

• 352320-15-1 5'-O-(4,4'-dimethoxytrityl)-5-[2-(4,4'-dimethoxytrityloxy)ethyl]-2'-deoxyuridine 
• 352320-16-2 3'-O-acetyl-5'-O-(4,4'-dimethoxytrityl)-5-[2-(4,4'-dimethoxytrityloxy)ethyl]-2'-deoxyuridine 
• 352353-42-5 acetic acid 8-[2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-8,13,15-trioxo-7,9,17-trioxa-1,14-diaza-8λ⁵-phospha-tricyclo[10.3.1.1^2,5]heptadec-12(16)-en-4-yl ester 
• 97975-03-6 1-(5-bromo-2,5-dideoxy-β-D-erythro-pentofuranosyl)-5-(2-bromoethyl)-1H,3H-pyrimidine-2,4-dione 
• 90301-64-7 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-(2-bromoethyl)pyrimidine-2,4(3H)dione 
• 90301-59-0 5-(2-chloroethyl)-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H,3H-pyrimidine-2,4-dione 
• 97975-02-5 1-(5-chloro-2,5-dideoxy-β-D-erythro-pentofuranosyl)-5-(2-chloroethyl)-1H,3H-pyrimidine-2,4-dione 

Relevant articles and documents

Essential factors for stabilization of the predominant C3′-endo conformation in dinucleoside phosphotriester derivatives with cyclonucleotide bridge structures at the downstream 3′-position

This paper describes the synthesis of conformationally constrained dinucleoside cyclic phosphotriester derivatives and related compounds, such as Tpc3Um (2), Tpc3dU (3), Tpc2dU (4), pc3dU (16), and pc2dU (25), where c2 and c3 refer to ethylene and propyle

5-(Haloalkyl)-2'-deoxyuridines: A Novel Type of Potent Antiviral Nucleoside Analogue

Syntheses of 5-(2-haloethyl)-2'-deoxyuridines, 5-(3-chloropropyl)-2'-deoxyuridines, and 5-(2-chloroethyl)-2'-deoxycytidine are described.The antiviral activities of these compounds were determined in cell culture against herpes simplex virus types 1 and 2