624-76-0

Basic information

• Product Name: 2-Iodoethanol
• Synonyms: 1-Hydroxy-2-iodethane;2-iodo-ethano;2-Iodoethylalcohol;Ethyleneidodhydrin;Iodoethanol;ETHYLENE IODOHYDRIN;2-IODOETHANOL;2-Iodo-1-ethanol
• CAS NO: 624-76-0
• Molecular Formula: C2H5IO
• Molecular Weight: 171.96
• EINECS: 210-861-6
• Product Categories: Alkohols;omega-Iodoalkanol;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Alcohols;C2 to C6;Oxygen Compounds
• Mol File: 624-76-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 120 °C
• Boiling Point: 85 °C25 mm Hg(lit.)
• Flash Point: 150 °F
• Appearance: Clear colorless to yellow-brown/Liquid
• Density: 2.205 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.513mmHg at 25°C
• Refractive Index: n20/D 1.572(lit.)
• Storage Temp.: 2-8°C
• PKA: 14.02±0.10(Predicted)
• Water Solubility: Soluble in water.
• Sensitive: Light Sensitive
• BRN: 1098258
• CAS DataBase Reference: 2-Iodoethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodoethanol(624-76-0)
• EPA Substance Registry System: 2-Iodoethanol(624-76-0)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-40
• Safety Statements: 45-36/37-28A
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• RTECS: KL3820000
• F: 8-10-23
• TSCA: T
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 624-76-0(Hazardous Substances Data)

Usage

Uses

2-Iodoethanol is used in the preparation of the neuroexcitants such as 4-dicarboxylic acid, alfa-kainic acid, 3-(carboxymethyl)pyrrolidine-2 and alfa-isokainic acid.

General Description

The standard molar enthalpy of 2-iodoethanol formation has been studied.

InChI:InChI=1/C2H5IO/c3-1-2-4/h4H,1-2H2

Upstream product

• 107-21-1 ethylene glycol 
• 74-85-1 ethene 
• 540-51-2 2-bromoethanol 
• 67-56-1 methanol 
• 111-91-1 bis(2-chloroethoxy)methane 
• 64-19-7 acetic acid 
• 98-81-7 1-bromovinylbenzene 
• 1072-53-3 ethyleneglycol sulfate 
• 2314-97-8 iodotrifluoromethane 
• 7553-56-2 iodine 
• 10403-66-4 2-hydroxy-ethylmercury ⁽¹⁺⁾; iodide 
• 4422-54-2 2-hydroxyethyl radical 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 94392-36-6 iodoethyl carbamate 
• 6367-98-2 (-)-(2R)-2-amino-3-(2-hydroxyethylsulfanyl)propanoic acid 
• 591-39-9 allophanic acid-(2-iodo-ethyl ester) 
• 83763-20-6 myristic acid-(2-iodo-ethyl ester) 
• 67-63-0 isopropyl alcohol 
• 78-92-2 iso-butanol 
• 625-48-9 2-nitro-1-ethanol 
• 75-07-0 acetaldehyde 
• 540-51-2 2-bromoethanol 
• 82547-01-1 2-(3,4-Diethoxy-phenyl)-5,7-diethoxy-3-(2-hydroxy-ethoxy)-chromen-4-one 
• 94768-56-6 3-(2-iodoethoxy)nonafluorocyclohexene 
• 94768-59-9 1-(2-iodoethoxy)nonafluorocyclohexene 
• 80240-11-5 iodo-2 ethylcarbamate de N-phenoxysulfonyle 
• 54555-84-9 benzyl iodoethyl ether 

Relevant articles and documents

UV Spectrum and the Kinetics and Reaction Pathways of the Self-Reaction of CH2CH2OH Radicals

CH2CH2OH radicals have been studied at room temperature by using a pulse radiolysis/kinetic absorption technique.The ultraviolet spectrum lies in the range 210-265 nm with a maximum absorption cross section of 2.0*10-18 cm2 molecule-1 at 210 nm.This technique has also been used to study the overall kinetics of the self-reaction of these radicals: 2CH2CH2OH (+M) --> (CH2CH2OH)2 (+M) (7a); 2CH2CH2OH (+M) --> CH3CHO + CH3CH2OH (7b), while product studies using gas chromatography have yielded information on the reaction pathways.A value of k7 = 5.6(+/-1.0)*10-11 cm3 molecule-1 s-1 and a branching ratio of k7a/(k7a + k7b) 0.88 have been measured at room temperature.

Carbodeoxygenation of biomass: The carbonylation of glycerol and higher polyols to monocarboxylic acids

Glycerol is converted to a mixture of butyric and isobutyric acid by rhodium- or iridium-catalysed carbonylation using HI as the co-catalyst. The initial reaction of glycerol with HI results in several intermediates that lead to isopropyl iodide, which upon carbonylation forms butyric and isobutyric acid. At low HI concentration, the intermediate allyl iodide undergoes carbonylation to give vinyl acetic acid and crotonic acid. Higher polyols CnH n+2(OH)n are carbonylated to the corresponding C n+1 mono-carboxylic acids. Copyright

Synthesis and physical properties of ferrocene derivatives (XXV) liquid crystallinity of 1,3-disubstituted ferrocene derivatives

Liquid crystallinity of 1,3-disubstituted ferrocene derivatives was studied by DSC and polarizing microscope. The name of the derivatives is 1,3-bis[-[4-(4-methoxyphenoxycarbonyl)phenoxy]alkyloxycarbonyl]ferrocene. Nine members from n = 2 to 10 were synthesized (n is carbon number of alkyl chain in the sample). All samples except n = 2 and 4 exhibited monotropic nematic liquid crystalline phase. In addition, smectic X (not yet completely identified) was also observed in n = 8 and 10. Liquid crystalline phase transition phenomena were discussed from a viewpoint of molecular shape. Copyright Taylor & Francis Group, LLC.