918321-20-7

Basic information

• Product Name: Methyl 5-aMino-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylate
• Synonyms: Methyl 5-aMino-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylate;Methyl 5-amino-4-fluoro-1-methyl-1H-1,3-benzodiazole-6-carboxylate;6-Amino-7-fluoro-3-methyl-benzimidazole-5-carboxylic acid methyl ester
• CAS NO: 918321-20-7
• Molecular Formula: C₁₀H₁₀FN₃O₂
• Molecular Weight: 223.2037032
• Mol File: 918321-20-7.mol

Chemical Properties

• Boiling Point: 389.9±52.0 °C(Predicted)
• Appearance: /
• Density: 1.45±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.57±0.10(Predicted)
• CAS DataBase Reference: Methyl 5-aMino-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-aMino-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylate(918321-20-7)
• EPA Substance Registry System: Methyl 5-aMino-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylate(918321-20-7)

Safety Data

• Hazardous Substances Data: 918321-20-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
Methyl 5-amino-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate is used as a building block in the pharmaceutical industry for the synthesis of various drugs and organic compounds. Its unique structure allows for the creation of new molecules with potential therapeutic effects.
Used in Antimicrobial Applications:
In the field of microbiology, Methyl 5-amino-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate is used as an antimicrobial agent. Its ability to inhibit the growth of certain microorganisms makes it a candidate for the development of new antimicrobial drugs to combat resistant strains.
Used in Antifungal Applications:
Similarly, in the realm of antifungal research, this compound is used to target and inhibit the growth of fungi. Its potential as an antifungal agent is being explored for applications in treating fungal infections and developing new antifungal medications.
Used in Drug Discovery and Development:
Methyl 5-amino-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate is utilized in the drug discovery and development process due to its unique properties and structural features. Researchers leverage its characteristics to design and develop new pharmaceuticals with improved efficacy and safety profiles.

Upstream product

• 918321-27-4 methyl 2,4,5-triamino-3-fluorobenzoate 
• 462-95-3 formaldehyde diethyl acetal 

Downstream Products

• 606144-02-9 methyl 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylate 
• 918321-22-9 6-(4-bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid Na salt 
• 606144-04-1 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylic acid 
• 1604812-72-7 C₁₅H₉BrF₂N₃O₂^(1-)*K⁽¹⁺⁾ 
• 606143-89-9 6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide 
• 1415564-99-6 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid 
• 1604812-73-8 C₁₈H₁₂BrF₂N₅O 
• 1604812-70-5 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid-(2-tert-butoxyethoxy)amide 

Relevant articles and documents

PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS

Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X1, X2, X5, R2 and R10 are as defined herein. Compounds of Formula Ia-1 and their synthetic intermediates can be used to prepare heterocyclic derivatives such as benzimidazole derivatives.