99745-88-7

Basic information

• Product Name: trans-1-hydroxy-2,7-diaminomitosene
• CAS NO: 99745-88-7
• Molecular Weight: 320.305
• Mol File: 99745-88-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: trans-1-hydroxy-2,7-diaminomitosene(CAS DataBase Reference)
• NIST Chemistry Reference: trans-1-hydroxy-2,7-diaminomitosene(99745-88-7)
• EPA Substance Registry System: trans-1-hydroxy-2,7-diaminomitosene(99745-88-7)

Safety Data

• Hazardous Substances Data: 99745-88-7(Hazardous Substances Data)

Usage

Uses

trans-1-Hydroxy-2,7-diamino Mitosene is derived from Mitomycin C (M371900), which is an antitumor antibiotic. It is antineoplastic.

Upstream product

• 103422-25-9 7-aminoaziridinomitosene 
• 50-07-7 mitomycin C 
• 57-14-7 N,N-Dimethylhydrazine 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 148091-11-6 mitomycin C 
• 958-09-8 2'-deoxy-D-adenosine 
• 362-76-5 2',3'-isopropylideneguanosine 

Relevant articles and documents

Synthesis of Mitomycin C and Decarbamoylmitomycin C N2 deoxyguanosine-adducts

Mitomycin C (MC) and Decarbamoylmitomycin C (DMC) - a derivative of MC lacking the carbamate on C10 - are DNA alkylating agents. Their cytotoxicity is attributed to their ability to generate DNA monoadducts as well as intrastrand and interstrand cross-lin

Studies on the reactivity of reductively activated mitomycin C

Mitomycin C (1a), a clinically significant antineoplastic antiobiotic, is considered to be the prototype of bioreductive alkylating agents. It has been reported that, in the absence of DNA, reductive activation of 1a furnished both solvolytic C(1) electro

Comparative reactivities of mitomycin C, 7-(N-piperidino)mitomycin, and mitomycin A. The role of the C(7)substituent

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