151213-43-3Relevant articles and documents
Racemisation of (1R, 6S)-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane using halogenated solvent in basic medium
Bhavsar, Jigar,Bhashkar, Bhuwan,Kumar, Anil
, p. 241 - 246 (2013/06/27)
A simple, highly rapid, efficient and eco friendly process for Racemisation of (1R, 6S)-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0] nonane in various halogenated solvents has been carried out as a base catalysed reaction to afford racemic mixture in excellent yields (80-95%) at temperature of or below 40°C. The base catalysed racemisation in halogenated solvent has an advantage of simple workup procedure, and use of less volume of halogenated solvent irrespective of type of solvent used in the reaction system.
PHENYLAMINOPYRIMIDINES AND THEIR USE AS RHO-KINASE INHIBITORS
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Page column 57,58, (2010/02/06)
The invention relates to the phenylaminopyrimidines of formula (I), wherein A, D, R1, R2, R3 and R4 are defined as in the description. The invention also relates to methods for producing said phenylaminopyrimidines and to their use for producing drugs for the treatment and/or the prophylaxis of diseases, especially cardiovascular diseases.
Quinolonecarboxylic acids
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, (2008/06/13)
The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a β-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives.
8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
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, (2008/06/13)
The invention relates to new 8-vinyl- and 8-ethinylquinolonecarboxylic acids, process for their preparation, and antibacterial agents and feed additives containing them.