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CHYMEX

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Name

CHYMEX

EINECS N/A
CAS No. 37106-97-1 Density 1.367g/cm3
PSA 115.73000 LogP 3.53410
Solubility N/A Melting Point 240-242°
Formula C23H20 N2 O5 Boiling Point 797.1°Cat760mmHg
Molecular Weight 404.422 Flash Point 435.9°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 37106-97-1 (BZ-TYR-4-ABZ-OH) Hazard Symbols N/A
Synonyms

Benzoicacid, 4-[[2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-, (S)-;4-(N-Benzoyl-L-tyrosyl)aminobenzoic acid; Bentiromide;Benzoyltyrosyl-p-aminobenzoic acid; N-Benzoyl-L-tyrosyl-p-aminobenzoate;N-Benzoyl-L-tyrosyl-p-aminobenzoic acid

 

CHYMEX Chemical Properties

Product Name: Chymex (CAS NO.37106-97-1)


Molecular Formula: C23H20N2O5
Molecular Weight: 404.42g/mol
Mol File: 37106-97-1.mol
Einecs: 253-349-8
Boiling point: 797.1 °C at 760 mmHg
Storage Temperature: Store at RT
Flash Point: 435.9 °C
Density: 1.367 g/cm3
Surface Tension: 66.8 dyne/cm
Enthalpy of Vaporization: 121.56 kJ/mol
Vapour Pressure: 8.46E-27 mmHg at 25°C
XLogP3-AA: 3.3
H-Bond Donor: 4
H-Bond Acceptor: 5

CHYMEX Uses

 Chymex (CAS NO.37106-97-1) is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. Headache and gastrointestinal disturbances have been reported in patients taking Chymex.

CHYMEX Toxicity Data With Reference

1.    

ipr-rat LD50:2000 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),181.
2.    

ivn-rat LD50:485 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),181.
3.    

ipr-mus LD50:1650 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),181.
4.    

ivn-mus LD50:1020 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),181.

CHYMEX Safety Profile

Moderately toxic by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

CHYMEX Specification

 Chymex ,its CAS NO. is 37106-97-1,the synonyms is (s)-4-((2-(Benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)benzoicacid ; (s)-P-(alpha-benzamido-p-hydroxyhydrocinnamamido)benzoicacid ; 4-((2-(Benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)-benzoicaci(s) ; 4-((2-(Benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl)amino)benzoicacid ; Benzoyltyrosyl-p-aminobenzoicacid ; Btpaba ; Chymex ; E-2663 .

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