The Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-, with the CAS registry number 87-44-5, is also known as (-)-trans-Caryophyllene. It belongs to the product categories of Sesqui-Terpenoids; Biochemistry; Terpenes; Terpenes (Others). Its EINECS number is 201-746-1. This chemical's molecular formula is C₁₅H₂₄ and molecular weight is 204.35. What's more, its systematic name is (1R,4E,9S)-4,11,11-Trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene. Its classification codes are: (1)Natural Product; (2)Skin / Eye Irritant. This chemical should be sealed in a brown glass bottle and stored in a cool place. It is one of the chemical compounds that contributes to the spiciness of black pepper. It may have antiinflammatory action. It can be prepared by separating the clove leaf oil , clove stem oil and cinnamon leaf oil. This substance is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems. It is usually found as a mixture with isocaryophyllene and α-humulene, a ring-opened isomer. Caryophyllene is notable for having a cyclobutane ring, a rarity in nature.

Physical properties of Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-, (1R,4E,9S)- are: (1)ACD/LogP: 6.416; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.42; (4)ACD/LogD (pH 7.4): 6.42; (5)ACD/BCF (pH 5.5): 44308.57; (6)ACD/BCF (pH 7.4): 44308.57; (7)ACD/KOC (pH 5.5): 73712.05; (8)ACD/KOC (pH 7.4): 73712.05; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Index of Refraction: 1.495; (13)Molar Refractivity: 66.596 cm³; (14)Molar Volume: 228.452 cm³; (15)Polarizability: 26.401×10^-24cm³; (16)Surface Tension: 29.7040004730225 dyne/cm; (17)Density: 0.894 g/cm³; (18)Flash Point: 104.917 °C; (19)Enthalpy of Vaporization: 48.603 kJ/mol; (20)Boiling Point: 268.359 °C at 760 mmHg; (21)Vapour Pressure: 0.0130000002682209 mmHg at 25°C.

Uses of Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-: it can be used to produce Caryophyllenoxid at the temperature of -20 °C. It will need reagents 30% H₂O₂, N-methylpyrrolidone/POCl₃, Na₂CO₃, 18-crown-6and solvent CH₂Cl₂ with the reaction time of 1 hour. The yield is about 77%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: C1(=C)\CC/C=C(/CC[C@@H]2[C@@H]1CC2(C)C)C
(2)Std. InChI: InChI=1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1
(3)Std. InChIKey: NPNUFJAVOOONJE-GFUGXAQUSA-N

The toxicity data is as follows: