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Cefeprime dihydrochloride

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Name

Cefeprime dihydrochloride

EINECS 827-945-9
CAS No. 107648-80-6 Density N/A
PSA 203.58000 LogP 1.19290
Solubility N/A Melting Point 150oC (dec.)
Formula C19H24N6O5S2.2(HCl) Boiling Point N/A
Molecular Weight 553.491 Flash Point N/A
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 107648-80-6 (Cefeprime dihydrochloride) Hazard Symbols N/A
Synonyms

Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-,chloride, monohydrochloride (9CI);Pyrrolidinium,1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-,chloride, monohydrochloride, [6R-[6a,7b(Z)]]-;Axepim;BMY 28142hydrochloride;Cepimax;Cepimex;Maxcef;Maxipime;

 

Cefeprime dihydrochloride Specification

The Cefepime dihydrochloride is an organic compound with the formula C19H24N6O5S2.2(HCl). The IUPAC name of this chemical is (6R,7R)-7-[[(2E)-2-(2-amino-1, 3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride hydrochloride. With the CAS registry number 107648-80-6, it is also named as pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, inner salt, hydrochloride (1:2). Besides, it is used in the treatment of a variety of bacterial infections including severe infection.

Physical properties about Cefepime dihydrochloride are: (1)ACD/LogP: -1.62; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -1.02; (4)ACD/LogD (pH 7.4): -1.07; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 12.42; (8)ACD/KOC (pH 7.4): 11.18; (9)#H bond acceptors: 11; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 7; (12)Polar Surface Area: 158.18 Å2.

You can still convert the following datas into molecular structure:
(1)SMILES: [Cl-].O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)C[N+]4(C)CCCC4)C(=O)O.Cl
(2)InChI: InChI=1/C19H24N6O5S2.2ClH/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H/b23-12-;;/t13-,17-;;/m1../s1
(3)InChIKey: XQQAUWFZBOTKFQ-MHRNPJSABL
(4)Std. InChI: InChI=1S/C19H24N6O5S2.2ClH/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H/b23-12-;;/t13-,17-;;/m1../s1
(5)Std. InChIKey: XQQAUWFZBOTKFQ-MHRNPJSASA-N

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