HSP e.g. HSP90 activators
HSP activators, particularly HSP90 activators, are compounds that promote the activity or expression of heat shock proteins (HSPs), specifically HSP90. Heat shock proteins are molecular chaperones that assist in the folding, assembly, and stabilization of other proteins under stress conditions, thereby maintaining cellular homeostasis. HSP90, in particular, plays a crucial role in regulating the conformation and function of many client proteins involved in cell signaling, growth, and survival pathways. By activating HSP90, these compounds enhance its chaperone function, facilitating the proper folding and stability of client proteins.
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