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Cas Database |
| Name |
Chlormezanone |
EINECS | 201-307-4 |
| CAS No. | 80-77-3 | Density | 1.391g/cm3 |
| PSA | 62.83000 | LogP | 2.63420 |
| Solubility | N/A | Melting Point |
114 °C |
| Formula | C11H12 Cl N O3 S | Boiling Point | 534.5oC at 760 mmHg |
| Molecular Weight | 273.74 | Flash Point | 277.1oC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: dilation of the pupils, ataxia (loss of muscle coordination), and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
4H-1,3-Thiazin-4-one,2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide (6CI,7CI,8CI); (?à)-Chlormezanone; (?à)-Fenarol;2-(4-Chlorophenyl)-3-methyl-4-metathiazanone-1,1-dioxide;2-(p-Chlorophenyl)-3-methyl-1,3-perhydrothiazin-4-one 1,1-dioxide;2-(p-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide;2-(p-Chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide; Alinam;Banabin-Sintyal; Chlormethazanone; Chlormethazone; Chlormezanone;Dichloromezanone; Fenarol; Lobak; Mio-Sed; Muskel Trancopal; NSC 169108;Phenarol; Rexan; Rilansyl; Rilaquil; Rilasol; Rilassol; Supotran; Suprotran;Tanafol; Trancopal; Trancote; Transanate; dl-Chlormezanone |
Article Data | 6 |
Chlormezanone Chemical Properties
IUPAC Name: 2-(4-Chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
Product Name: 2-(4-Chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
The MF of Chlormezanone (CAS NO.80-77-3) is C11H12ClNO3S.
The MW of Chlormezanone (CAS NO.80-77-3) is 273.74.
Synonyms of Chlormezanone (CAS NO.80-77-3): (±)-Chlormezanone ; 2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide ; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide ; 2-(p-Chlorophenyl)perhydro-3-methyl-1,3-thiazin-4-one 1,1-dioxide ; 4H-1,3-Thiazin-4-one, 2- (4-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide ; Dichloromethazanone ; Lobak
Form: A white crystalline powder
Index of Refraction: 1.58
EINECS: 201-307-4
Density: 1.391 g/ml
Flash Point: 277.1 °C
Boiling Point: 534.5 °C
Melting Point: 114 °C
Merck: 2106
Chlormezanone Uses
Chlormezanone (CAS NO.80-77-3) is used as weak antipsychotic. With a calm, stable and central role in muscle relaxation.also used for fear of mental stress, chronic fatigue, anxiety, excitement, and irritation caused by certain diseases such as not sleeping. Due to the importance of muscle relaxation, with the analgesic can be used for back acid, neck hard, bone pain, spinal and limb pain and rheumatoid joint pain.
Chlormezanone Production
Raw materials: 4-Chlorobenzaldehyde-->3-Mercaptopropionic acid
Preparation Products: whitener WG for wool-->Ketamine hydrochloride
Chlormezanone Toxicity Data With Reference
| 1. | orl-man TDLo:157 mg/kg:EYE,CNS | BMJOAE British Medical Journal. 292 (1986),732. | ||
| 2. | orl-rat LD50:605 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 130 (1961),280. | ||
| 3. | ipr-rat LD50:370 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 17 (1967),242. | ||
| 4. | orl-mus LD50:600 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 9 (1975),601. | ||
| 5. | ipr-mus LD50:570 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 17 (1967),242. | ||
| 6. | scu-mus LD50:322 mg/kg | APTOA6 Acta Pharmacologica et Toxicologica. 19 (1962),247. | ||
| 7. | orl-dog LD50:500 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),168. | ||
| 8. | ipr-dog LD50:500 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),168. | ||
| 9. | ipr-gpg LD50:600 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),168. |
Chlormezanone Safety Profile
Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: dilation of the pupils, ataxia (loss of muscle coordination), and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.Safety information of Chlormezanone (CAS NO.80-77-3):
RTECS XJ1050000
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