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| Name |
Coben |
EINECS | N/A |
| CAS No. | 24699-40-9 | Density | N/A |
| PSA | 19.37000 | LogP | 4.31400 |
| Solubility | N/A | Melting Point |
183-185° |
| Formula | C19H25 N3 . Cl H | Boiling Point | N/A |
| Molecular Weight | 331.93 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2-Pyridinemethanamine,N-phenyl-N-[2-(1-piperidinyl)ethyl]-, monohydrochloride (9CI); Piperidine,1-[2-[N-(2-pyridylmethyl)anilino]ethyl]-, monohydrochloride (8CI); Coben;N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride; Picoperidaminehydrochloride; Picoperine hydrochloride |
Coben Chemical Properties
Product Name: Coben
Molecular Formula: C19H25N3
Molecular Weight: 295.4219 g/mol
Mol File: 24699-40-9.mol
Index of Refraction: 1.596
Molar Refractivity: 92.41 cm3
Molar Volume: 271.3 cm3
Surface Tension: 48.6 dyne/cm
Boiling point: 448.5 °C at 760 mmHg
Flash Point: 225.1 °C
Density: 1.088 g/cm3
Surface Tension: 48.6 dyne/cm
Enthalpy of Vaporization: 70.71 kJ/mol
Vapour Pressure: 3.08E-08 mmHg at 25 °C
Coben Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 25mg/kg (25mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
| dog | LDLo | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
| mouse | LD50 | intraperitoneal | 55500ug/kg (55.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
| mouse | LD50 | intravenous | 10mg/kg (10mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
| mouse | LD50 | oral | 195mg/kg (195mg/kg) | Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 29, Pg. 310, 1970. | |
| mouse | LD50 | subcutaneous | 142mg/kg (142mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
| rat | LD50 | intraperitoneal | 69mg/kg (69mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
| rat | LD50 | intravenous | 11500ug/kg (11.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
| rat | LD50 | oral | 740mg/kg (740mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
| rat | LD50 | subcutaneous | 480mg/kg (480mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
Coben Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.
Coben Specification
Coben ,its CAS NO. is 24699-40-9,the synonyms is -(2-(N-(2-Pyridylmethyl)anilino)ethyl)piperidine hydrochloride ; 1-(2-(Phenyl(2-pyridylmethyl)amino)ethyl)piperidine hydrochloride ; 2-Pyridinemethanamine, N-phenyl-N-(2-(1-piperidinyl)ethyl)-, monohydrochloride ; N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride ; N-(2-Piperidinoethyl)-N-(2-pyridylmethyl)aniline hydrochloride ; N-(2-Pyridylmethyl)-N-phenyl-N-2-(piperidinoethyl)amine hydrochloride ; N-Phenyl-N-(2-pyridylmethyl)-2-piperidinoethylamine hydrochloride ; Picoperidamine hydrochloride ; Picoperine HCl ; Picoperine hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, monohydrochloride ; TAT-3 hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, hydrochloride .
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